Results 51 to 60 of about 683,252 (345)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Ethambutol optic neuropathy in the extended anti-tubercular therapy regime: A systematic review

open access: yesIndian Journal of Ophthalmology, 2023
The extended use of ethambutol beyond 2 months for treating tuberculosis has increased risk of optic neuropathy. We performed a systematic review of studies evaluating optic neuropathy in extended ethambutol use since 2010 and compared the outcome with a
Swapnali Sabhapandit   +6 more
doaj   +1 more source

Visual field defects in obstructive hydrocephalus [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1982
Four cases are described in which visual field defects followed enlargement of the third ventricle. Three were due to aqueduct stenosis while in one case a left cerebellar hemisphere tumour was discovered. The visual field defects comprised a unilateral scotoma, bilateral scotomata and, in two patients, incongruous bitemporal hemianopia.
P R, Humphrey   +2 more
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Multi-line Adaptive Perimetry (MAP): A New Procedure for Quantifying Visual Field Integrity for Rapid Assessment of Macular Diseases. [PDF]

open access: yes, 2018
PurposeIn order to monitor visual defects associated with macular degeneration (MD), we present a new psychophysical assessment called multiline adaptive perimetry (MAP) that measures visual field integrity by simultaneously estimating regions associated
Biles, Mandy K   +5 more
core   +1 more source

Expert system for analysis of casting defects - ESVOD [PDF]

open access: yes, 2015
The powerful tool for defect analysis is an expert system. It is a computer programme based on the knowledge of experts for solving the quality of castings. We present the expert system developed in the VSB-Technical University of Ostrava called 'ESWOD'.
Elbel, Tomáš   +2 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

The Impact of Visual Field Loss on Driving Skills: A Systematic Narrative Review

open access: yesBritish and Irish Orthoptic Journal, 2019
Purpose: To review the evidence on the impact of visual field loss on skills required for driving. Methods: A literature search was undertaken using a systematic approach.
Gemma Patterson   +3 more
doaj   +1 more source

Health economics analysis of visual acuity and visual field test in Cushing's disease based on risk factors

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2023
Objective To screen risk factors related to visual acuity and visual field defects in patients with Cushing's disease, and based on risk factors to analyze health economics.
FENG Shan⁃shan
doaj   +1 more source

Automated objective characterization of visual field defects in 3D [PDF]

open access: yes, 2006
A method and apparatus for electronically performing a visual field test for a patient. A visual field test pattern is displayed to the patient on an electronic display device and the patient's responses to the visual field test pattern are recorded.
Fink, Wolfgang
core   +1 more source

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