Results 41 to 50 of about 694,239 (264)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Association between visual field damage and corneal structural parameters

open access: yesScientific Reports, 2021
The main goal of this study is to identify the association between corneal shape, elevation, and thickness parameters and visual field damage using machine learning.
Alexandru Lavric   +4 more
doaj   +1 more source

Hourglass-AVSR: Down-Up Sampling-based Computational Efficiency Model for Audio-Visual Speech Recognition [PDF]

open access: yesarXiv, 2023
Recently audio-visual speech recognition (AVSR), which better leverages video modality as additional information to extend automatic speech recognition (ASR), has shown promising results in complex acoustic environments. However, there is still substantial space to improve as complex computation of visual modules and ineffective fusion of audio-visual ...
arxiv  

Dynamics of test particles in the five-dimensional Gödel spacetime [PDF]

open access: yesPhys. Rev. D 98, 044050 (2018), 2018
We derive the complete set of geodesic equations for massive and massless, charged test particles of a five-dimensional, rotating and charged solution of the Einstein-Maxwell-Chern-Simons field equations in five-dimensional minimal gauged supergravity and present their analytical solutions.
arxiv   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

A Field Study of the Impact of Indoor Lighting on Visual Perception and Cognitive Performance in Classroom

open access: yesApplied Sciences, 2020
In this field study, a series of psychophysical tests were conducted to investigate the impact of indoor lighting on students’ visual perception and cognitive performance.
Qiang Liu   +7 more
doaj   +1 more source

Dynamics of test particles in the five-dimensional, charged, rotating EMCS spacetime [PDF]

open access: yesPhys. Rev. D 94, 124003 (2016), 2016
We derive the complete set of geodesic equations for massive and massless test particles of a five-dimensional, charged, rotating black hole solution of the Einstein-Maxwell-Chern-Simons field equations in five-dimensional minimal gauged supergravity and present their analytical solutions in terms of Weierstra{\ss}' elliptic functions.
arxiv   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1898-1909, December 2022., 2022
Abstract Objectives Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by a fully automated immunoassay platform, and brain β‐amyloid (Aβ ...
Hisashi Nojima   +9 more
wiley   +1 more source

Diagnostic Accuracies of a Smartphone-Based Fundus Photography and Tablet-Based Visual Field Testing

open access: yesPhilippine Journal of Ophthalmology, 2022
Objective: We determined the diagnostic accuracies of the mydriatic, monoscopic, iPhone 6s+ optic nerve photographs with a 20D lens and the Melbourne Rapid Fields (MRF) visual fields iPad application.
Patricia Anne S. Tecson MD, MBA   +2 more
doaj  

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