Results 61 to 70 of about 8,270,013 (310)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Visual function, visual attention and mobility performance in low vision [PDF]

open access: yes, 2008
Purpose: The aim of this study was to determine if useful field of view (UFV) measures help to predict aspects of orientation and mobility in people with visual impairment.
Lovie-Kitchin, Janette E.   +1 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

P336: Resolving missing heritability by iterative multidisciplinary and organ-specific reanalysis

open access: yesGenetics in Medicine Open, 2023
Ehsan Ullah   +11 more
doaj   +1 more source

Differentiation of monocytes and polarized M1/M2 macrophages from human induced pluripotent stem cells

open access: yesSTAR Protocols
Summary: Here, we present a protocol to differentiate induced pluripotent stem cell (iPSC) into adherent hematopoietic progenitors that release floating CD14+ CD45+ monocytes into the culture medium.
Tea Soon Park   +7 more
doaj   +1 more source

Visual Resources Association Constitution & Bylaws

open access: yes, 2020
The complete texts of the Visual Resources Association's Constitution, as amended, and the Association Bylaws, as revised, effective December 11 ...
Kohl, Allan T.
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Ganoderma lucidum polysaccharide attenuates retinal ischemia-reperfusion injury by regulating microglial M1/M2 polarization, suppressing neuroinflammation and inhibiting JAK2/STAT3 pathway

open access: yesBiochemistry and Biophysics Reports
Retinal ischemia-reperfusion (RIR) injury is implicated in the pathogenesis of numerous retinal degenerative disorders, resulting in visual impairment or even blindness in millions of individuals worldwide.
Guangyu Zhu   +5 more
doaj   +1 more source

Dynamic Measures of Visual Function and Their Relationship to Self-Report of Visual Functioning

open access: yesInvestigative Opthalmology & Visual Science, 2006
The purpose of this analysis was to determine whether dynamic measures of vision, such as dynamic acuity and motion threshold, are independently associated with self-reported difficulty in activities involving vision.Data were used from the third round of the Salisbury Eye Evaluation (n = 1198), a longitudinal, population-based study of older adults ...
Ellen E, Freeman   +3 more
openaire   +2 more sources

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