Results 51 to 60 of about 2,240,353 (293)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Study on the Method of Matched Splice Grafting for Melon Seedlings Based on Visual Image

Agriculture, 2022
Due to the cutting mechanism of the existing grafting machine, it cannot adjust the cutting angle in real time, resulting in low fitting precision on the cutting surfaces between the rootstocks and scion seedlings and, thus, seriously affecting the ...
Pengyun Xu, Tong Zhang, Liping Chen, Wenqian Huang, Kai Jiang   +4 more
doaj   +1 more source

Visual Comfort Assessment for Stereoscopic Image Retargeting

, 2018
In recent years, visual comfort assessment (VCA) for 3D/stereoscopic content has aroused extensive attention. However, much less work has been done on the perceptual evaluation of stereoscopic image retargeting.
An, Ping, Chen, Zhibo, Zhou, Wei, Zhou, Ya   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Automated Detection and Biomarker Identification Associated with the Structural and Functional Progression of Glaucoma on Longitudinal Color Fundus Images

Applied Sciences
The diagnosis of primary open-angle glaucoma (POAG) progression based on structural imaging such as color fundus photos (CFPs) is challenging due to the limited number of early biomarkers, as commonly determined by clinicians, and the inherent ...
Iyad Majid, Zubin Mishra, Ziyuan Chris Wang, Vikas Chopra, Dale Heuer, Zhihong Jewel Hu   +5 more
doaj   +1 more source

Relating visual and semantic image descriptors [PDF]

, 2004
This paper addresses the automatic analysis of visual content and extraction of metadata beyond pure visual descriptors. Two approaches are described: Automatic Image Annotation (AIA) and Confidence Clustering (CC). AIA attempts to automatically classify
Cooke, Eddie, Le Borgne, Hervé, O'Connor, Noel E., Sirot, Joel, Stauder, Jurgen   +4 more
core  

Image Reconstruction from Bag-of-Visual-Words

, 2015
The objective of this work is to reconstruct an original image from Bag-of-Visual-Words (BoVW). Image reconstruction from features can be a means of identifying the characteristics of features.
Harada, Tatsuya, Kato, Hiroharu
core   +1 more source

Aesthetic preference for art emerges from a weighted integration over hierarchically structured visual features in the brain [PDF]

, 2020
It is an open question whether preferences for visual art can be lawfully predicted from the basic constituent elements of a visual image. Moreover, little is known about how such preferences are actually constructed in the brain.
Iigaya, Kiyohito, O'Doherty, John P., Tanwisuth, Koranis, Wahle, Iman A., Yi, Sanghyun   +4 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source