Results 61 to 70 of about 695,432 (264)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Visual acuity measures do not reliably detect childhood refractive error--an epidemiological study. [PDF]

, 2012
PURPOSE: To investigate the utility of uncorrected visual acuity measures in screening for refractive error in white school children aged 6-7-years and 12-13-years.
Nicola S Logan, Saunders, Kathryn J., Rudnicka, AR, Saunders, KJ, O'Donoghue, Lisa, Alicja R Rudnicka, Rudnicka Alicja R., McClelland Julie F., Logan, Nicola S., Julie F McClelland, Lisa O'Donoghue, Saunders Kathryn J., Rudnicka, Alicja R., McClelland, Julie F., Logan, NS, McClelland, JF, O'Donoghue, L, O'Donoghue Lisa, Logan Nicola S., Kathryn J Saunders   +19 more
core   +1 more source

Treatment Outcomes and Clinical Characteristics in Children with Amblyopia at Naresuan University

Journal of Health Science and Medical Research (JHSMR), 2022
Objective: To evaluate the visual outcomes of amblyopia treatment and identify the characteristics of children with newly diagnosed amblyopia. Material and Methods: This is a retrospective study of children newly diagnosed with amblyopia from January ...
Mayuree Montriwet
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Barriers to follow-up for pediatric cataract surgery in Maharashtra, India: How regular follow-up is important for good outcome. The Miraj Pediatric Cataract Study II

Indian Journal of Ophthalmology, 2014
Background: Regular follow up and amblyopia treatment are essential for good outcomes after pediatric cataract surgery. Aim: To study the regularity of follow-up after cataract surgery in children and to gauge the causes of poor compliance to follow up ...
Parikshit Gogate, Shailbala Patil, Anil Kulkarni, Ashok Mahadik, Rahin Tamboli, Rekha Mane, Rishiraj Borah, G V Rao   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Teaching Visual Literacy Skills in a One-Shot Session

, 2020
Just as one-shot information literacy sessions can be implemented in college classes to improve students’ research capabilities, similarly-styled sessions on image research can increase their visual literacy skills.
Schoen, Molly J.
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Ecological determinants of blindness in Nigeria: the Nigeria National Blindness and Visual Impairment Survey. [PDF]

, 2011
OBJECTIVE: To determine the prevalence and causes of visual loss in different ecological zones across Nigeria. METHODS: A population-based survey using multi-stage, stratified, cluster random sampling with probability proportional to size comprising a ...
Abubakar, Tafida, Rabiu, MM, Kyari, Fatima, Nigeria National Blindness and Visual Impairment Study Group, Gudlavalleti, Murthy VS, Gilbert, CE, Sivasubramaniam, Selvaraj, Gudlavalleti, Murthy V S, Gilbert, C E, Rabiu, M M   +9 more
core   +1 more source