Results 81 to 90 of about 695,432 (264)

Infestation of the lacrimal sac by Rhinosporidium seeberi: A clinicopathological case report

Indian Journal of Ophthalmology, 2013
Rhinosporidium seeberi , till recently known as a fungus, has been reclassified as a protistan parasite. It infects humans and many animal species. The authors describe a rare case of oculosporidiosis with involvement of the lacrimal sac exhibiting ...
Bipasha Mukherjee, Ashwin Mohan, V Sumathi, Jyotirmay Biswas   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Optical coherence tomography parameters predictive of visual outcome after anti-VEGF therapy for retinal vein occlusion

, 2016
Akiko Fujihara-Mino, Yoshinori Mitamura, Naoki Inomoto, Hiroki Sano, Kei Akaiwa, Kentaro Semba Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan Purpose: To determine the optical ...
Semba K, Mitamura Y, Sano H, Akaiwa K, Inomoto N, Fujihara-Mino A   +5 more
core  

Visual and Skill Effects on Soccer Passing Performance, Kinematics and Outcome Estimations

, 2015
The role of visual information and action representations in executing a motor task was examined from a mental representations approach. High-skill (n = 20) and low-skill (n = 20) soccer players performed a passing task to two targets at distances of 9 ...
Itay Basevitch (4217308), Paul Ward (3271302), Itay eBasevitch, Gershon Tenenbaum, Gershon eTenenbaum, Ward, Paul, William M. Land (16669701), William M Land, Paul Ward, Paul eWard, Itay Basevitch, Land, William M., Basevitch, Itay, William M. Land, Gershon Tenenbaum (801938), Tenenbaum, Gershon   +15 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Time-resolved influences of functional DAT1 and COMT variants on visual perception and post-processing [PDF]

, 2012
BACKGROUND: Dopamine plays an important role in orienting and the regulation of selective attention to relevant stimulus characteristics. Thus, we examined the influences of functional variants related to dopamine inactivation in the dopamine transporter
Laucht, Manfred (Prof. Dr.), Rellum Thomas, Thomas Rellum, Resch, Franz, Stephan Bender, Brandeis, Daniel, Banaschewski, Tobias, Laucht Manfred, Bender, Stephan, Rietschel, Marcella, Jennen-Steinmetz, Christine, Freitag, Christine M., Treutlein, Jens, Jens Treutlein, Rellum, Thomas, Daniel Brandeis, Brandeis Daniel, Tobias Banaschewski, Jennen-Steinmetz Christine, Christine Freitag, Bender Stephan, Banaschewski Tobias, Manfred Laucht, Freitag, Christine, Franz Resch, Rietschel Marcella, Marcella Rietschel, Resch Franz, Christine Jennen-Steinmetz, Laucht, Manfred, Treutlein Jens, Freitag Christine   +31 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Visual outcome of cataract surgery at Gondar University Hospital Tertiary Eye Care and Training Center, North West Ethiopia

, 2017
Mohammed Seid Hussen,1 Kbrom Legesse Gebreselassie,1 Mohammed Assen Seid,2 Gizachew Tilahun Belete1 1Department of Optometry, 2Department of Clinical Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Background ...
Seid MA, Hussen MS, Gebreselassie KL, Belete GT   +3 more
core  

Preoperative visual acuity among cataract surgery patients and countries' state of development: a global study. [PDF]

, 2011
OBJECTIVE: To describe the preoperative surgical case mix among patients undergoing cataract extraction and explore associations between case mix, country level of development (as measured by the Human Development Index, HDI) and cataract surgery rates ...
Razavi, H, Turner, EL, Claire Gilbert, Robert J Lindfield, Robert Lindfield, Lindfield, Robert J, Shaheen Shah, Elizabeth Turner, Gilbert, Clare E, Int Eye Res, N, International Eye Research Network, Shah, SP, Claire E Gilbert, Razavi, Hessom, Shaheen P Shah, Hessom Razavi, Elizabeth L Turner, Gilbert, CE, Shah, Shaheen P, Turner, Elizabeth L, Lindfield, RJ   +20 more
core   +1 more source