Results 91 to 100 of about 695,432 (264)
Rectifying calibration error of Goldmann applanation tonometer is easy!
Purpose: Goldmann applanation tonometer (GAT) is the current Gold standard tonometer. However, its calibration error is common and can go unnoticed in clinics. Its company repair has limitations.
Nikhil S Choudhari +8 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Visual outcome of intravitreal ranibizumab for exudative age-related macular degeneration: timing and prognosis [PDF]
Handan Canan,1 Selçuk Sizmaz,2 Rana Altan-Yaycioğlu,1 Çağla Saritürk,3 Gürsel Yilmaz41Department of Ophthalmology, Adana Teaching and Medical Research Center, Baskent University School of Medicine, 2Department of Ophthalmology ...
Canan H. +14 more
core +1 more source
Effect of wet-laboratory training on resident performed manual small-incision cataract surgery
Purpose: The aim of this study was to study the effect of wet-laboratory training on the surgical outcome of resident performed manual small-incision cataract surgery (MSICS).
Soumya Ramani +2 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Visual outcome after emergency surgery for open globe eye injury in Japan
Ai Toride,1,2 Hiroshi Toshida,1 Asaki Matsui,1 Yusuke Matsuzaki,1 Rio Honda,1,3 Toshihiko Ohta,1 Akira Murakami3 1Department of Ophthalmology, Juntendo University Shizuoka Hospital, Shizuoka, 2Department of Ophthalmology, Juntendo University Nerima ...
Toride A +6 more
core
Hospital admissions in older people with visual impairment in Britain. [PDF]
BACKGROUND: We aimed to assess the risk of hospital admission associated with visual impairment in a representative sample of older people living in the community in Britain. DESIGN: Prospective study of hospital admission in a population-based sample of
Astrid E Fletcher +8 more
core +1 more source
Visual outcomes of the surgical rehabilitative process following open globe injury repair
BackgroundThe path of rehabilitation of an eye after open globe injury (OGI) may require multiple additional secondary surgeries after the initial repair.
Richard N. Sather +6 more
doaj +1 more source
Human intraretinal myelination: Axon diameters and axon/myelin thickness ratios
Purpose: Human intraretinal myelination of ganglion cell axons occurs in about 1% of the population. We examined myelin thickness and axon diameter in human retinal specimens containing myelinated retinal ganglion cell axons.
Thomas FitzGibbon, Zoran Nestorovski
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source

