Results 71 to 80 of about 9,486,727 (312)

Visual Resources Outreach: Successes and Challenges in a New Role

open access: yes, 2020
More than ever, visual resources are intrinsic to the teaching mission and visual literacy goals of universities. However, in many cases potential users are unaware of how libraries can assist in the implantation and integration of visual resources into ...
Kline, Heather
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Growth, Visual Quality, and Morphological Responses of 12 Viburnum Taxa to Saline Water Irrigation

open access: yesHortScience, 2020
Viburnums are widely used in gardens and landscapes throughout the United States. Although salinity tolerance varies among plant species, research-based information is limited on the relative salt tolerance of viburnum species.
Youping Sun   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Visual Resources Association Constitution & Bylaws

open access: yes, 2020
The complete texts of the Visual Resources Association's Constitution, as amended, and the Association Bylaws, as revised, effective December 11 ...
Kohl, Allan T.
core  

The "Life Cycle of Visual Assets": Advocating for the Profession

open access: yes, 2023
The VRA Identity Task Force was formed in 2018 in response to the Visual Resources Association Strategic Plan (2018-2022), which recommended that the VRA reflect upon its identity with regard to both its legacy and future.
Whitlow, Betha, Lucarelli, Carolyn
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Rethinking Visual Resources Centers in the Digital Age: Case Studies at the University of Georgia and the University of Michigan

open access: yes, 2020
Visual Resource Centers are facing many challenges—and opportunities—in the wake of the digital era. Since their beginnings as slide libraries, many VRCs have had missions across college campuses to serve the image needs of faculty in art-related fields.
Baron, Courtney L., Schoen, Molly J.
core  

Impact of soft and rigid gas-permeable contact lenses on visual performance in mesopic conditions

open access: yesIndian Journal of Ophthalmology
Context: Evaluation of visual quality in soft and rigid gas-permeable contact lens wearers, with an emphasis on twilight vision. Purpose: To assess the visual acuity and visual performance at dusk before and after soft and rigid gas-permeable contact ...
Iva Krolo   +6 more
doaj   +1 more source

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