Results 81 to 90 of about 9,486,727 (312)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
The New Interactive: Reimagining Visual Collections as Immersive Environments
, 2020 Emerging technologies and shared standards have opened up new avenues for the curation and presentation of data in archives and published research. Among their many benefits, these developments have made collections across archives more accessible, and ...
Emanuel, Jeffrey P. +2 more
core
Quality Assessments of Visualizations [PDF]
, 2018 Dimensionality reduction techniques reduce the dimensions of the input space to facilitate the exploration of structures in high-dimensional data. Two general dimensionality reduction approaches exist: manifold learning and projection. Manifold learning methods attempt to find sub-spaces in which the high-dimensional distances are preserved.
openaire +1 more source
A Quality Metric for Visualization of Clusters in Graphs [PDF]
, 2019 Traditionally, graph quality metrics focus on readability, but recent studies show the need for metrics which are more specific to the discovery of patterns in graphs. Cluster analysis is a popular task within graph analysis, yet there is no metric yet explicitly quantifying how well a drawing of a graph represents its cluster structure.
Meidiana, Amyra +3 more
openaire +4 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
2004 Texas Water Quality Inventory [PDF]
, 2004 Waller Creek Working ...
Texas Commission on Environmental Quality
core +1 more source
Indian Journal of OphthalmologyPurpose: To observe the effects of visual neuroplasticity training on visual perception, visual quality, and macular blood flow in patients with concomitant strabismus postoperatively.
Min Tian +7 more
doaj +1 more source
Türk Oftalmoloji Dergisi, 2013 Purpose: To evaluate the effects of different lens designs on visual quality among soft spherical contact lens users. Material and Method: Forty eyes of twenty patients from our contact lens unit were included in this study.
Mustafa Demir +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source