Results 91 to 100 of about 1,191,394 (309)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The effect of a single high dose of caffeine on the visual reaction time of young elite soccer players at rest and during varying intensities of physical activity

open access: yesСпортивная медицина: наука и практика
Aim: To examine the effect of a single high dose of caffeine on visual reaction time (VRT) in young elite soccer players at rest and under different intensity physical exercise conditions.Materials and methods: In a double-blind, placebo-controlled ...
T. M. Vakhidov   +5 more
doaj   +1 more source

A Role for the prefrontal cortex in supporting singular demonstrative reference [PDF]

open access: yes, 2019
One of the most pressing questions concerning singular demonstrative mental contents is what makes their content singular: that is to say, what makes it the case that individual objects are the representata of these mental states.
de Carvalho, Felipe Nogueira   +1 more
core   +1 more source

Distinct phase-amplitude couplings distinguish cognitive processes in human attention [PDF]

open access: yes, 2018
Spatial attention is the cognitive function that coordinates the selection of visual stimuli with appropriate behavioral responses. Recent studies have reported that phase-amplitude coupling (PAC) of low and high frequencies covaries with spatial ...
Chacko, Ravi V.   +8 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Visual Tracking in Development and Aging

open access: yesFrontiers in Neurology, 2017
A moving target is visually tracked with a combination of smooth pursuit and saccades. Human visual tracking eye movement develops through early childhood and adolescence, and declines in senescence.
Jun Maruta   +6 more
doaj   +1 more source

Crowding and visual search in high functioning adults with autism spectrum disorder [PDF]

open access: yes, 2010
Purpose: Individuals with autism spectrum disorder have demonstrated faster reaction times when searching for objects in a visual scene. One possible explanation for this observation is that the influence of crowding may not be as strong within this ...
Bowler, D. M.   +3 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Visual Reaction Time and High-Speed Ball Games

open access: yesPerception, 1987
Laboratory measures of visual reaction time suggest that some aspects of high-speed ball games such as cricket are ‘impossible’ because there is insufficient time for the player to respond to unpredictable movements of the ball. Given the success with which some people perform these supposedly impossible acts, it has been assumed by some commentators ...
openaire   +3 more sources

Sense of agency primes manual motor responses [PDF]

open access: yes, 2009
Perceiving the body influences how we perceive and respond to stimuli in the world. We investigated the respective effects of different components of bodily representation - the senses of ownership and agency - on responses to simple visual stimuli ...
Haggard, P., Longo, Matthew R.
core   +1 more source

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