Results 41 to 50 of about 1,316,844 (266)

A theoretical model reveals specialized synaptic depressions and temporal frequency tuning in retinal parallel channels

open access: yesFrontiers in Computational Neuroscience, 2022
In the Outer Plexiform Layer of a retina, a cone pedicle provides synaptic inputs for multiple cone bipolar cell (CBC) subtypes so that each subtype formats a parallelized processing channel to filter visual features from the environment.
Liuyuan He   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease

open access: yesFrontiers in Neuroscience, 2021
Despite decades of research, disease-modifying treatments of Parkinson’s disease (PD), the second most common neurodegenerative disease worldwide, remain out of reach.
Lien Veys   +11 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Human Color Perception: The Impact of Color Perception on Fine-Grained Emotion Prediction in Movie and Television Videos

open access: yesSensors
This article investigates the impact of visual color perception on fine-grained emotion prediction in videos, analyzing the contribution of color perception features in fine-grained emotion prediction.
Shuang Wang   +6 more
doaj   +1 more source

Opsin genes: research perspectives with Neotropical cichlids (Perciformes: Cichlidae) and their relevance in floodplain studies

open access: yesActa Scientiarum: Biological Sciences, 2016
Vision not only plays an important role in the behavior and exploration capacity of new ecology niches but also influences the evolution of species exposed to the heterogeneity of light.
Thomaz Mansini Carrenho Fabrin   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Lens Thickness in Infants and Children with Cataracts

open access: yesOphthalmology Science
Purpose: The purpose of this study was to determine the association between lens thickness and cataract in participants aged 0 to 5 years. Design: This was a prospective, multicenter, case–control study.
Libby Wei, MD   +13 more
doaj   +1 more source

Retinal Inflammation, Oxidative Stress, and Vascular Impairment Is Ablated in Diabetic Mice Receiving XMD8-92 Treatment

open access: yesFrontiers in Pharmacology, 2021
The global number of diabetics continues to rise annually. As diabetes progresses, almost all of Type I and more than half of Type II diabetics develop diabetic retinopathy.
Scott J. Howell   +9 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy