Results 131 to 140 of about 3,122,559 (347)
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Towards Coordination-Intensive Visualization Software [PDF]
, 2003 Most coordination realizations in current visualization systems are ''last-minute'' ad-hoc and rely on the richness of the chosen implementation language. Moreover, very few visualization models implicitly consider coordination.
Boukhelifa, Nadia +2 more
core
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Visualization in spatial modeling [PDF]
, 2006 This chapter deals with issues arising from a central theme in contemporary computer modeling - visualization. We first tie visualization to varieties of modeling along the continuum from iconic to symbolic and then focus on the notion that our models ...
Batty, M, Steadman, P, Xie, Y
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Visualization of Valvular and Myocardial Calcification by Planigraphy [PDF]
, 1954 Louis A. Soloff +2 more
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Visualization of Publication Impact [PDF]
, 2016 Measuring scholarly impact has been a topic of much interest in recent years. While many use the citation count as a primary indicator of a publications impact, the quality and impact of those citations will vary.
Louppe, Gilles +2 more
core
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Mental Visualizations and External Visualizations [PDF]
, 2019 Mental Visualizations and External Visualizations Mary Hegarty (hegarty@psych.ucsb.edu) Department of Psychology, University of California, Santa Barbara Santa Barbara, CA 93106 USA Recent advances in computer technology and graphics have made it possible to produce powerful visualizations of scientific phenomena and more abstract information. There is
openaire +3 more sources