Results 191 to 200 of about 3,122,559 (347)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

IMPROVED STAIN FOR VISUALIZATION OF AZOTOBACTER ENCYSTMENT [PDF]

, 1964
G. R. Vela, Orville Wyss
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Letter to the Editor Regarding: "AOSpine Consensus Paper on Nomenclature for Working-Channel Endoscopic Spinal Procedures" by Hofstetter et al. [PDF]

Global Spine J
Moura Gonçalves V, Gonçalves V.
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Clear Vision, Clear Savings: Enhancing Efficiency in Minimally Invasive Surgery. [PDF]

JSLS
Dhingra J, Beinart N, Ahmed A, Patel M, Ameerah A, Srinivasan M, Idelson CR, Uecker JM.   +7 more
europepmc   +1 more source

Visualization of Cardiovascular System With Radiopaque Media [PDF]

, 1960
Alfred Halpern, Saul S. Samuels
openalex   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

A decentralized privacy-preserving XR system for 3D medical data visualization using hybrid biometric cryptosystem. [PDF]

Sci Rep
Sharma S, Das D, Chaudhury S.
europepmc   +1 more source

THE HISTOCHEMICAL VISUALIZATION OF PROTEIN-BOUND SULFHYDRYL GROUPS WITH AN AZOMERCURIAL REAGENT

, 1964
Milton B. Engel, Eugenio Zerlotti
openalex   +1 more source