Results 121 to 130 of about 1,755,266 (312)

Visual Analysis of Amino Acid Radiation Protection Research Based on CiteSpace

open access: yesShipin gongye ke-ji
Objective: To conduct a bibliometric analysis of the literature in the field of amino acid radiation protection over the past decade using CiteSpace software, exploring the formation, development, hotspots, and trends in this domain.
Tingyang LI   +7 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Speculative practices : utilizing InfoVis to explore untapped literary collections

open access: yes, 2015
Funding: Canadian Social Sciences and Humanities Research CouncilIn this paper we exemplify how information visualization supports speculative thinking, hypotheses testing, and preliminary interpretation processes as part of literary research.
Hinrichs, Uta   +5 more
core   +1 more source

Sciatic nerve injury treated by acupuncture: a bibliometric study and visualization analysis

open access: yesFrontiers in Neurology
ObjectiveSciatic nerve injuries often lead to severe pain and motor dysfunction, causing serious impact on patients’ quality of life. Acupuncture, as one of the main therapies in traditional Chinese medicine, is gradually gaining attention in the field ...
Yan Wang   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Visualization-Panel for Provenance Data

open access: yes, 2008
Today’s IT-systems are becoming more difficult. Their relationship together grows as well as their complexity. Currently a main requirement is for people to trust more in the results and have a better understanding of the functionality.
Kunde, Markus
core  

Progressive Data Analysis and Visualization

open access: yes, 2019
International audienceWe live in an era where data is abundant and growing rapidly; databases storing big data sprawl past memory and computation limits, and across distributed systems.
Fisher, Danyel   +3 more
core   +1 more source

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