Results 131 to 140 of about 1,658,167 (263)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Application of multi-omics in systemic autoimmune rheumatic diseases: a bibliometric and visualization analysis. [PDF]
Front ImmunolCheng L, Tang Z, Li M, Huang C.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Research Hotspots and Trends in Ciliopathies: A Bibliometric and Visualization Analysis. [PDF]
Biomed Res IntDong Q, Zhu J, Liu J, Xu H.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
New trends and hotspots in Sepsis-associated encephalopathy research: a bibliometric and visualization analysis. [PDF]
Front Aging NeurosciWang Y, Zheng L, Ye F.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The impact of aerobic exercise on cardiopulmonary function: A bibliometric and visualization analysis. [PDF]
Medicine (Baltimore)Dou L.
europepmc +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Journal of Multidisciplinary HealthcareQin Lin,1,2,* Linfeng Liu,3,* Mengxue Fu,2,* Kanlun Chen,4,* Ling Li,1 Minmin Jiang,1 Jijun Wu5 1Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, People’s Republic of China; 2College of Nursing and ...
Lin Q +6 more
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