Results 51 to 60 of about 1,755,266 (312)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Hotspots and Tendencies of Energy Optimization Based on Bibliometric Review
Due to the highly recent innovations in energy optimization research, this study presents a systematic overview of the area, exposing gaps and interesting directions for future research.
Issam Hanafi +3 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Towards Ubiquitous Brushing for Information Visualization [PDF]
Brushing is a collection of techniques to dynamically query and directly select elements on the visual display. Such interaction allows the user to explore the visualization, to interactively select a subset of points and see how these changes are ...
Wright, M.A.E., Roberts, J.C.
core +1 more source
BackgroundThe incidence and mortality rates of stroke are escalating due to the growing aging population, which presents a significant hazard to human health.
Fangcun Li +8 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
CoViCAD : comprehensive visualization of coronary artery disease
We present novel, comprehensive visualization techniques for the diagnosis of patients with Coronary Artery Disease using segmented cardiac MRI data.
Gerritsen, F.A. +6 more
core +1 more source
Artificial intelligence is a branch of computer science that attempts to understand the essence of intelligence and produce a new intelligent machine capable of responding in a manner similar to human intelligence. Research in this area includes robotics,
Teng Long +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

