Results 81 to 90 of about 1,267,577 (241)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis

Frontiers in Oncology
ObjectivePrediction models, which estimate disease or outcome probabilities, are widely used in cancer research. This study aims to identify hotspots and future directions of cancer-related prediction models using bibliometrics.MethodsA comprehensive ...
Siyu Li, Wenrui Li, Xiaoxiao Wang, Wanyi Chen   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

New progress in the theoretical research and application of pulsating heat pipe

工程科学学报, 2019
As a new type of heat transfer device with a unique working mechanism, the pulsating heat pipe (PHP) has high heat transfer efficiency, high resistance capability to drying out, and good environmental adaptability.
LI Qing-feng, WANG Ya-nan, HE Xin, LIAN Chen, LI Hua   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

New techniques for experimental generation of two-dimensional blade-vortex interaction at low Reynolds numbers [PDF]

An experimental investigation of two dimensional blade vortex interaction was held at NASA Langley Research Center. The first phase was a flow visualization study to document the approach process of a two dimensional vortex as it encountered a loaded ...
Booth, E., Jr., Yu, J. C.
core   +1 more source

Jigsaw: investigative analysis on text document collections through visualization [PDF]

, 2008
This article describes the Jigsaw system for helping investigative analysis across collections of text documents. Jigsaw provides multiple visualizations of the documents and the entities within them to help investigators discern embedded stories and ...
Görg, C., Stasko, J.
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Research on the Applicability of Hybrid RANS/LES Models to Predict the Flow Behavior in Bulb Tubular Pump Under Rated and Stall Conditions

Energy Science & Engineering
The investigation into the internal flow characteristics of the bulb tubular pump device has important practical significance for improving both optimal design and operation stability.
Longyue Sun, Qiang Pan, Linlin Geng, Desheng Zhang, Xavier Escaler   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source