Results 41 to 50 of about 157,338 (257)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Object Detection for the Enrichment of Semantic 3D City Models with Roofing Materials [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Semantically rich 3D city models play a vital role in a variety of applications, such as urban planning. Enhancing these models with currently unavailable attributes, such as roof material types, can unlock new opportunities to tackle pressing challenges,
L. Arzoumanidis, S. H. Nguyen, L. Johannsen, F. Rothaut, W. Li, W. Li, Y. Dehbi   +6 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Active Forms of Conducting European Studies: Experience, Analysis, Conclusions

Horyzonty Wychowania, 2021
RESEARCH OBJECTIVE: The purpose of the paper is to assess the efficiency of the active forms (Quiz, One Pager, the World Café, Visualization: Mind Mapping, Interactive lecture-discussion) used within the European studies for PhD students on ensuring ...
Svitlana Sysoieva, Olena Lokshyna, Olena Protsenko, Ilona Tryhub   +3 more
doaj   +1 more source

The Effect of Instructor-Produced Videos as Supplemental Material for Training Visual Screening Procedures in Occupational Therapy Education

Journal of Occupational Therapy Education, 2019
The aim of this study was to explore student perceptions of instructor-produced videos to enhance knowledge, self-efficacy, and clinical skill with administering visual screening procedures. The video library, hosted by Vimeo™, consisted of 26 videos, with an average video duration less than 90 seconds.
Grieves, Holly, Pickens, Noralyn Davel, Young, Tracy, Smith, Theresa M.   +3 more
openaire   +4 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Empowering Indonesian EFL Teachers: The Transformative Impact of Visual Literacy Training on Teaching Materials

International Journal of Learning, Teaching and Educational Research
Within the contemporary landscape dominated by visual media, educators' proficiency in visual literacy is crucial for effective pedagogy, particularly in English language instruction. This research aims to explore the effects of visual literacy training on the capability of English teachers at Kalam Kudus Elementary School, Bali, to create innovative ...
Bachtiar Bachtiar, Irasuti Irasuti
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Construct validity of UroSim® simulator for learning transurethral resection of bladder tumor

Urology Research and Practice, 2020
Objective: There is an increasing trend to incorporate Simulator-based training in urology residency programs. The study was designed to determine the construct validity of UroSim® for that we compared the performance of transurethral resection of ...
Ahsan Rafi, Wajahat Aziz, Mohammad H. Ather   +2 more
doaj   +1 more source