Results 51 to 60 of about 528,981 (304)
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Evaluation of Respiratory Capacity of Pottery and Ceramic Workers in Lalejin-Hamadan
For evaluation of respiratory capacities, the amount of VC(Vital Capacity), FVC (Forced Vital Capacity), FEV (Forced Expiratory Volume in one second) were measured in 221 pottery, ceramic, slip, molder workers in Lalejin ...
Abdolrahman Bahrami, Hosein Mahjub
doaj
VITAL CAPACITY OF THE LUNGS OF TRAMPOLINE GYMNASTS AGED 10-13
Vital capacity (VC) tests are an important tool in assessing the functioning of the respiratory system. Low levels of vital capacity can indicate health problems such as asthma, chronic obstructive pulmonary disease, and other respiratory conditions ...
Bartłomiej Patryk Hes +1 more
doaj +1 more source
The correlation of vital capacity readings and clinical examination: with special reference to vital capacity observations in obese subjects [PDF]
After taking many hundreds of observations of vital lung capacity, the following conclusions are arrived at :-(1) Individual variations present one of the greatest drawbacks to the value of vital capacity readings.It is necessary to know the ...
Rolt, John B.
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Maximum phonation times and vital capacity in dysphonic women
Objective: to verify the correlation between vital capacity and maximum phonation times of /ė/ (unvoiced) and /s/, as well as compare and relate them with the professional voice use and age in women with functional or organic-functional dysphonia ...
Carla Aparecida Cielo (5910803) +3 more
core +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Difference between slow vital capacity and forced vital capacity in the diagnosis of airflow limitation [PDF]
Carlos Alberto de Castro Pereira +6 more
doaj +3 more sources
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source

