Results 61 to 70 of about 491,563 (259)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Change of spinal range of motion, lungs volume and pain evaluation inpatients with ischemic heart disease after bypass surgery [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The purpose of this study is to evaluate the changes in range of motion in the joints of the spine in the sagittal plane, motion of the chest, lung vital capacity, minute respiratory rate as well as evaluation of pain intensity in men after cardiac ...
Bolach Eugeniusz.   +3 more
doaj  

FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KAPASITAS VITAL PARU PADA PEKERJA PENGGILINGAN DIVISI BATU PUTIH DI PT. SINAR UTAMA KARYA

open access: yesUnnes Journal of Public Health, 2014
Tujuan penelitian ini untuk mengetahui faktor-faktor yang berhubungan dengan kapasitas vital paru pekerja penggilingan divisi batu putih PT. Sinar Utama Karya. Jenis penelitian ini Explanatory Research dengan pendekatan cross-sectional.
Yuma Anugrah
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

VITAL CAPACITY OF THE LUNGS OF TRAMPOLINE GYMNASTS AGED 10-13

open access: yesScience of Gymnastics Journal
Vital capacity (VC) tests are an important tool in assessing the functioning of the respiratory system. Low levels of vital capacity can indicate health problems such as asthma, chronic obstructive pulmonary disease, and other respiratory conditions ...
Bartłomiej Patryk Hes   +1 more
doaj   +1 more source

Kadar Debu terhadap Kapasitas Vital Paru pada Masyarakat di Sekitar PT Semen Baturaja

open access: yesJurnal Kesehatan, 2018
Function disorders were generally occurred due to individual factors and environmental factors. One of the industries that experienced a lot of development was PT. Semen Batu Raja which is located in Kelurahan Way Lunik.
Sri Indra Trigunarso   +2 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

TÜRKİYE’DEKİ MİNİK FUTBOLCULARDA REAKSİYON ZAMANI, VİTAL KAPASİTE DEĞERLERİ VE LATERİZASYON DAĞILIMINDA SOLAKLIK SORUNU

open access: yesSpormetre Beden Eğitimi ve Spor Bilimleri Dergisi, 2007
Bu çalışmada amaç, Türkiye’deki minik futbolcularda reaksiyon zamanı ve vital kapasite değerlerinin belirlenmesi ve Türkiye’de sol kulvarda oynayabilecek futbolculardaki yetersizlik sorununun kaynağını tespit etmektir.
Osman İmamoğlu, Ertan Kılcıgil
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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