Matrix: a complex amalgam of structures and functions in tumor microenvironment
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis+3 more
wiley +1 more source
BackgroundNonmotor symptoms are very common in neurodegenerative diseases. In patients suffering from amyotrophic lateral sclerosis (ALS), olfactory dysfunction was first reported more than 20 years ago; however, its pathophysiological correlates and ...
René Günther+10 more
doaj +1 more source
Genome-wide association analysis identifies six new loci associated with forced vital capacity [PDF]
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and ...
A Bill Musk+216 more
core +4 more sources
Automated rapidplan model validation using Eclipse scripting API
Abstract RapidPlan offers efficiency gains and quality improvements in treatment planning. Prior to its use in the clinic, it requires an extensive validation procedure in which established clinical plans and those generated by the model are compared. The manual iterative nature of this process is resource intensive, as numerous iterations are required
Bradley Beeksma+2 more
wiley +1 more source
Acute lung affection in an endurance-trained man under amiodarone medication
Patients undergoing treatment with amiodarone can develop severe pulmonary side effects. This effect, which is often highly underestimated, can lead to dyspnea, pneumonitis, and further fibrosis.
Saurbier, Bernward+4 more
doaj
Impact of respiratory motion on dose distribution in SIB‐SBRT for lung cancer
Abstract Purpose Respiratory motion is a major source of dose uncertainty in lung cancer radiotherapy. The dose distribution of simultaneous integrated boost‐stereotactic body radiotherapy (SIB‐SBRT) is inhomogeneous and is significantly impacted by respiratory motion for lung cancer. The effect of respiratory motion on SIB‐SBRT was investigated with a
Lingling Liu+7 more
wiley +1 more source
Correlation between Forced Expiratory Volume One Second and Vital Capacity with VO2 Maximum
Background: Medical students need to cope with their tight schedule, which also demand a good physical fitness to do those activities. Insufficient leisure time and exhausting activities impede students’ capacity on having routine physical exercise to ...
Siti Khadijah Rahmania+2 more
doaj +1 more source
THE INFLUENCE OF BREATHING EXERCISE TOWARD FEV 1 AND KVP AMONG THE JUNIOR HIGH SCHOOL STUDENTS IN YOGYAKARTA [PDF]
This paper aims to reveal the influence of respiratory exercise on the forced one second volume (FEVi) and lung vital capacity (KVP) of the female student in MTs Mu'alimat Yogyakarta.
Sudarko, Rumpis Agus
core
Wildlife reintroduction: considerations of habitat quality at the release site. [PDF]
BACKGROUND: Assessing the suitability of a habitat prior to the release of animals is vital. Proper assessment of the flora will allow reintroduction programmes to determine whether the area will be capable of supporting the released animals in the long ...
core +1 more source
Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1
ABSTRACT Objective Valosin‐containing protein (VCP)‐associated multisystem proteinopathy 1 (MSP1) is caused by variants in the VCP gene. MSP1 results in various phenotypes including progressive myopathy, Paget's disease of bone, frontotemporal dementia, amyotrophic lateral sclerosis, and parkinsonism, among others.
Lindsay N. Alfano+15 more
wiley +1 more source