Results 31 to 40 of about 1,212 (259)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relational Encounters and Vital Materiality in the Practice of Craft Work [PDF]

open access: yesOrganization Studies, 2019
Practice-based studies of organization have drawn attention to the importance of the body as a site of knowledge and knowing. However, relational encounters between bodies and objects, and the affects they generate, are less well understood in organization studies.
Emma Bell, Sheena J. Vachhani
openaire   +3 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

SEXUALITY IN A CONTEXT OF SPECULATIVE POSTHUMANISM: HUMAN-POSTHUMAN RUPTURES AND DISCONNECTIONS

open access: yesВісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії, 2019
In this article human-posthuman ruptures and disconnections both in comprehension and in practices, as well as the possibility of epistemological contingency contemporaneously are investigated.
Nataliia V. Zahurska
doaj   +1 more source

A Vital Challenge to Materialism

open access: yesPhilosophy, 2016
AbstractLife poses a threat to materialism. To understand the phenomena of animate nature, we make use of a teleological form of explanation that is peculiar to biology, of explanations in terms of what I call the ‘vital categories’ – and this holds even for accounts of underlying physico-chemical ‘mechanisms’.
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

A Bataillean Perspective on Migration and the Nation-State: The Politics of Active Matter as an Irreducible Force

open access: yesFelsefe Arkivi
This study explores the relationship between migration and classical materialist reductionist approaches to matter through Bataille’s concept of base materialism which focuses on the idea of formless matter.
Ahmet Er
doaj   +1 more source

Giving Wands Their Due

open access: yesFafnir, 2023
Magical objects are legion in Harry Potter. Among them, wands are the most magical and the most taken for granted. Wands are usually seen as tools, but no tool is only a tool.
Ian McLaughlin
doaj  

Vital Materialism and the Problem of Ethics in the Radical Enlightenment [PDF]

open access: yesPhilosophica, 2013
From Hegel to Engels, Sartre and Ruyer (Ruyer, Revue Philosophique 116(7–8):28–49, 1933), to name only a few, materialism is viewed as a necropolis, or the metaphysics befitting such an abode; many speak of matter’s crudeness, bruteness, coldness or stupidity.
openaire   +2 more sources

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