Results 201 to 210 of about 1,662,591 (252)

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Continuous vs Intermittent Postoperative Vital Sign Monitoring: A Cluster Randomized Crossover Trial.

JAMA Netw Open
Khanna AK, O'Connell NS, Saha AK, Hicks MH, Weller RS, Harris L, Cusson BD, Faris A, Huffman CS, Segal S, Wells BJ, Kirkendall ES, Sessler DI.   +12 more
europepmc   +1 more source

Neuropsychiatric outcomes in sepsis: A vital sign worth monitoring. [PDF]

World J Psychiatry
Middleton ML, Lucke-Wold B.
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Vital sign-based Early Warning Scores in low- and middle-income countries: a systematic review of clinical effectiveness and implementation challenges. [PDF]

Glob Health Action
Jansen NJ, Veldhuis LI.
europepmc   +1 more source

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source

Radar-Based Monitoring: A Proof of Principle Study in a Piglet Model for a Novel Approach in Non-Contact Vital Sign Monitoring. [PDF]

Sensors (Basel)
Goedicke-Fritz S, Schmiech D, Thull R, Kaiser E, Körbel C, Laschke MW, Marnach A, Müller S, Tutdibi E, Nourkami-Tutdibi N, Weber R, Zemlin M, Diewald AR.   +12 more
europepmc   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

Reliability of contactless vital sign measurement algorithms for use in drone-based mass casualty triage. [PDF]

Sci Rep
Tayfur İ, Şimşek P, Akgül EC, Ateş YŞ, Gunduz A, Bal M, Üstübioğlu A, Bayramoğlu B, Altinarik S, Ryan B, Donahoo MJ, Karakoç A.   +11 more
europepmc   +1 more source