An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li +11 more
wiley +1 more source
The menstrual cycle: an overlooked vital sign in psychiatry? [PDF]
Marwick KF +3 more
europepmc +1 more source
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu +10 more
wiley +1 more source
SiViS: Simulated multi-patient physiological clinical states for advanced vital sign radar monitoring research. [PDF]
Reyes KM +7 more
europepmc +1 more source
Identification of vital sign trajectory phenotypes and treatment response heterogeneity in critically ill patients with ischemic stroke: A multicenter study with external validation. [PDF]
Wang L, Wang D, Tang B, Duan J, Huang J.
europepmc +1 more source
Pain as the Fifth Vital Sign: Challenges in Managing Cancer-Related Pain. [PDF]
Faiman B.
europepmc +1 more source
Social Determinants of Health: The Impact of This Overlooked Vital Sign. [PDF]
Vrtikapa K, Hoque Urmy F, Hoque F.
europepmc +1 more source
Workflow, Alarm Notification and Technology Acceptance of Continuous, Wearable-Based Vital Sign Monitoring on A Neurosurgical Ward-A Pilot Feasibility Study. [PDF]
Alsolivany J +9 more
europepmc +1 more source

