Results 91 to 100 of about 360,171 (329)
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao +7 more
wiley +1 more source
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Exam‐level analysis of lecture capture viewing and student exam performance
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Este estudio aporta diversa documentación sobre la familia, estudios y otras cuestiones biográficas de Antonio de Torquemada a partir del rastreo en los archivos históricos.
Jesús Fernando Cáseda Teresa
doaj +1 more source
El aprendizage basado en competencias en la formación musical de educadores de infantil [PDF]
p. 313-328El presente trabajo se enmarca dentro de una concepción constructivista del aprendizaje donde se presta especial atención al desarrollo de las diferentes competencias que serán vitales en su futuro profesional. Se propone la elaboración de
Varela, Nídia Fernández
core
Respiratory syncytial virus: Clinical and epidemiological pattern in pediatric patients admitted to a children’s hospital between 2000 and 2013 [PDF]
INTRODUCTION: Respiratory syncytial virus (RSV) is the major causative organism associated with acute lower respiratory tract infections in children.The objective of this study was to describe the clinical and epidemiological pattern of RSV and identify ...
Bakir, Julia +8 more
core +1 more source
The Basis of Individuality in Organisms. A Defense of Vitalism [PDF]
H. V. Neal
openalex +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source

