Results 91 to 100 of about 68,446 (339)

Effects of Some Commercial Enzymes in the Deinking of Newsprint [PDF]

open access: yes, 1972
The trend of industry, in general, today is one of recycling. This is brought about as a means of conserving our dwindling natural resources and to help abate the pollution problem.
Prickett, James O.
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

La conception ternaire corps/esprit/âme dans la pensée médicale au cours des âges

open access: yesCahiers d'Études du Religieux- Recherches Interdisciplinaires, 2013
The progressive emergence of a rational medical knowledge did not prevent links with philosophy (mainly Plato and Aristotle) and theology. The tripartition body/soul/spirit (the meaning of these terms varying according to the different periods) is one of
Thierry Lavabre-Bertrand
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Une passion genrée ? L’itinéraire de la compassion dans la littérature médico-philosophique moderne (1660-1780)

open access: yesNoctua
Compassion is mentioned and studied within 17th- and 18th-century philosophical and medical literature as an emotional phenomenon. The advent of iatrophysics in explaining bodily functions, and the adoption of vitalist approaches, appear to have strongly
Elena Muceni
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Raízes do vitalismo francês: Bordeu e Barthez, entre Paris e Montpellier The roots of French vitalism: Bordeu and Barthez, between Paris and Montpellier

open access: yesHistória, Ciências, Saúde: Manguinhos, 2011
Analisa as propostas classificadas como vitalistas, formuladas na França no século XVIII. Contextualiza a tradição da escola médica de Montpellier, abordando as concepções fisiológico-médicas de Théophile de Bordeu.
Silvia Waisse   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy