Results 71 to 80 of about 3,763 (272)

De la palabra al género: un itinerario

open access: yesFilología, 2014
La obra de Ana María Barrenechea se caracteriza por una atención a los modos de leer. Aquí se propone, más allá de las adhesiones disciplinares y a partir de unas determinadas experiencias de trabajo (es decir: de vida comunitaria) una relectura de la ...
Daniel Link
doaj  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

“THE OMNIPOTENT CALL OF SPRING”: IVAN FRANKO’S POETIC CYCLE “SPRING SONGS” AS A FOLK TRADITION AND AN AUTHORIAL TRANSFORMATION OF THE GENRE

open access: yesSlovo i Chas
The paper offers a comprehensive analysis of Ivan Franko’s poetic cycle “Spring Songs” (“Vesnianky”), which presents an innovative reinterpretation of the folk song tradition.
Алла Швець
doaj   +1 more source

La conception ternaire corps/esprit/âme dans la pensée médicale au cours des âges

open access: yesCahiers d'Études du Religieux- Recherches Interdisciplinaires, 2013
The progressive emergence of a rational medical knowledge did not prevent links with philosophy (mainly Plato and Aristotle) and theology. The tripartition body/soul/spirit (the meaning of these terms varying according to the different periods) is one of
Thierry Lavabre-Bertrand
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Cinematic Vitalism

open access: yes
This book argues that there are constitutive links between early twentieth-century German and French film theory and practice, on the one hand, and vitalist conceptions of life in biology and philosophy, on the other.
Pollmann, Inga
core   +1 more source

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