Results 51 to 60 of about 1,287 (253)
The avant-garde of “titans” as a stage in the transgression of the Romantic movement
The article is the second part of the author’s study of the avant-garde of the early 20th century, or early avant-garde, which is considered the third stage in the development of the Romantic movement - not in the narrow art-historical sense, but in a ...
A. E. Kapishin
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Materiality and Satire in Marvell’s “The Last Instructions to a Painter”
In “The Last Instructions to a Painter,” Marvell articulates and then critiques the idealizing ethos of the Stuart regime by using a rhetoric of corporeality to reveal the limitations and falsity of this ideological vision, and to censure the corruption ...
William Fitzhenry
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Compassion is mentioned and studied within 17th- and 18th-century philosophical and medical literature as an emotional phenomenon. The advent of iatrophysics in explaining bodily functions, and the adoption of vitalist approaches, appear to have strongly
Elena Muceni
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Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
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Le parti pris des choses : sur quelques apories onto-épistémiques du New Materialism
The theoretical movement known as New Materialism, which emerged in the early 2000s, saw not only the return of ontology, but also the affirmation of a materialism in which all oppositions and contradictions would dissolve.
Charles Wolfe
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
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Epigênese e epigenética: as muitas vidas do vitalismo ocidental
Resumo A análise da história e dos usos contemporâneos dos termos epigênese, atribuído a Aristóteles, e epigenética, criado no século XX pelo biólogo C. H.
Gláucia Silva +1 more
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