Results 91 to 100 of about 1,086,541 (315)

De la palabra al género: un itinerario

open access: yesFilología, 2014
La obra de Ana María Barrenechea se caracteriza por una atención a los modos de leer. Aquí se propone, más allá de las adhesiones disciplinares y a partir de unas determinadas experiencias de trabajo (es decir: de vida comunitaria) una relectura de la ...
Daniel Link
doaj  

After Affirmation, or, Being a Loser: On Vitalism, Sacrifice, and Cinders

open access: yes, 2015
What could it mean to hesitate before life? To be unwilling or unable to affirm existence? And who or what would suggest such a thing? What type of monster would embrace sadness over joy, despair over hope, failure over success?
P. Harrison
semanticscholar   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

La conception ternaire corps/esprit/âme dans la pensée médicale au cours des âges

open access: yesCahiers d'Études du Religieux- Recherches Interdisciplinaires, 2013
The progressive emergence of a rational medical knowledge did not prevent links with philosophy (mainly Plato and Aristotle) and theology. The tripartition body/soul/spirit (the meaning of these terms varying according to the different periods) is one of
Thierry Lavabre-Bertrand
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

The discreet charm of eighteenth-century vitalism and its avatars [PDF]

open access: yes, 2015
The species of vitalism discussed here, to immediately rule out two possible misconceptions, is neither the feverish cosa mentale found in ruminations on ‘biopolitics’ and fascism – where it alternates quickly between being a form of evil and a form of ...
Wolfe, Charles T.
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Do psíquico ao somático: notas sobre a reconfiguração do self contemporâneo

open access: yesHistória, Ciências, Saúde: Manguinhos
Resumo O artigo examina a passagem de uma compreensão psicológica da pessoa para uma compreensão somática/cerebral. A discussão centra-se na dualidade que marca a cultura ocidental moderna, entre a visão iluminista e racionalista do mundo e a visão ...
Jane Russo
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

THE VITALITY OF A NATION* [PDF]

open access: yesBritish Journal of Inebriety, 1906
n ...
openaire   +1 more source

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