Results 91 to 100 of about 189,973 (301)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

“We Don't Normally Go Down This Avenue; This Is Normally Taboo”: Using Co‐Design to Develop a Training Intervention for Spiritual Health in Primary Care

Health Expectations
Introduction Spiritual health is an important component of holistic health and social care provision; however, previous research highlights a training gap in this area.
Ishbel Orla Whitehead, Mark Adley, Alexandra Thompson, Elizabeth Westhead, Marina Politis, Philip Mordue, Amy O'Donnell, Barbara Hanratty   +7 more
doaj   +1 more source

Urban Food Takeaway Vitality: A New Technique to Assess Urban Vitality

, 2021
As one of the most important criteria for measuring the quality of urban life and the environment, urban vitality has become the focus of urban-related research and related disciplines with an increasing number of advocates for the rapid and harmonious ...
Ming Li, Chunshan Zhou, Bahram Zikirya, Xiong He   +3 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Efficacy of progressive resistance training intensities and adequate dietary protein intake for community-dwelling frail older adults (TEAMS study), protocol for a randomised controlled trial

BMC Geriatrics
Background Progressive Resistance Training (PRT) and adequate dietary protein are crucial for preventing and managing sarcopenia and frailty in older adults.
M. Benali, J. van den Helder, E. J.M. Biersteker, J. D. Schoufour, P. J.M. Weijs, M. Tieland   +5 more
doaj   +1 more source

Faculty Vitality in the Changing Research University, December 1996

, 1996
University of Minnesota. Faculty Consultative Committee. Working Group on Faculty Vitality, 1996. (1996). Faculty Vitality in the Changing Research University, December 1996. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/
University of Minnesota. Faculty Consultative Committee. Working Group on Faculty Vitality, 1996
core  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Protocol for the Delirium and Cognitive Impact in Dementia (DECIDE) study: A nested prospective longitudinal cohort study

BMC Geriatrics, 2017
Background Delirium is common, affecting at least 20% of older hospital inpatients. It is widely accepted that delirium is associated with dementia but the degree of causation within this relationship is unclear.
Sarah J. Richardson, Daniel H.J. Davis, Blossom Stephan, Louise Robinson, Carol Brayne, Linda Barnes, Stuart Parker, Louise M. Allan   +7 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source