Results 21 to 30 of about 112,055 (160)

Alpha-Synuclein Post-translational Modifications: Implications for Pathogenesis of Lewy Body Disorders

Frontiers in Aging Neuroscience, 2021
Lewy Body Disorders (LBDs) lie within the spectrum of age-related neurodegenerative diseases now frequently categorized as the synucleinopathies. LBDs are considered to be among the second most common form of neurodegenerative dementias after Alzheimer's
Nelson de Oliveira Manzanza, Lucia Sedlackova, Raj N. Kalaria   +2 more
doaj   +1 more source

Systematic transcriptomic analysis and temporal modelling of human fibroblast senescence

Frontiers in Aging
Cellular senescence is a diverse phenotype characterised by permanent cell cycle arrest and an associated secretory phenotype (SASP) which includes inflammatory cytokines.
R.-L. Scanlan, L. Pease, H. O’Keefe, A. Martinez-Guimera, L. Rasmussen, J. Wordsworth, D. Shanley   +6 more
doaj   +1 more source

Lust op leeftijd: tijd om waarderend te luisteren naar ouderen over seksualiteit

Tijdschrift voor Gerontologie en Geriatrie
Het is hoogtijd om het hardnekkige zwijgen over seksualiteit op latere leeftijd te doorbreken. In de ouderenzorg blijft seksualiteit vaak een taboe, ondanks toenemende aandacht voor autonomie en persoonsgerichte zorg.
Jana Kerssies, Elena Bendien
doaj   +1 more source

Healthy Lifestyle Interventions in General Practice: Part 10: Lifestyle and Arthritic Conditions - Osteoarthritis

South African Family Practice, 2010
Chronic musculoskeletal disease is one of the most common causes of disability worldwide with considerable economic impact in health care. Osteoarthritis (OA) is the most common chronic musculoskeletal disease affecting a large proportion of the ...
Martin P. Schwellnus, D.N. Patel, C. Nossel, M. Dreyer, S. Whitesman, E.W. Derman   +5 more
doaj   +1 more source

Liaison Old Age Psychiatry Service in a Medical Setting: Description of the Newcastle Clinical Service

Nursing Research and Practice, 2011
Liaison Old Age Psychiatry services (LOAP) have begun to emerge in the UK and further development of the service is supported by the latest health policies.
E. B. Mukaetova-Ladinska, G. Cosker, M. Coppock, M. Henderson, Y. Ali Ashgar, A. Hill, A. Scully, D. Robinson, K. Sells, S. Brotherton, C. Lowthian   +10 more
doaj   +1 more source

Care priorities for stroke patients developing cognitive difficulties: a Delphi survey of UK professional views

BMC Health Services Research, 2020
Background Post stroke cognitive difficulties are common but generally prioritised below other impairments. In the UK, clinical guidelines recommend a holistic review at six-months post-stroke including an assessment of cognitive function.
Eugene Y. H. Tang, Louise Robinson, Catherine Exley, Darren Flynn, Blossom C. M. Stephan, Christopher Price   +5 more
doaj   +1 more source

Safety and tolerability of adjunct non-invasive vagus nerve stimulation in people with parkinson’s: a study protocol

BMC Neurology, 2023
Background Parkinson’s disease (PD) is the fastest growing neurological condition worldwide. Recent theories suggest that symptoms of PD may arise due to spread of Lewy-body pathology where the process begins in the gut and propagate transynaptically via
Hilmar P. Sigurdsson, Heather Hunter, Lisa Alcock, Ross Wilson, Ilse Pienaar, Elizabeth Want, Mark R. Baker, John-Paul Taylor, Lynn Rochester, Alison J. Yarnall   +9 more
doaj   +1 more source

Vitalism

, 2011
Vitalism is typically presented as the belief – scientific, metaphysical, poetic and other – in the uniqueness of Life, presented as a ‘substance’, ‘force’, or ‘principle’. As such it is a frequently criticized theory, often in caricatural forms, where a model of the living being (notably of organism), embryo development, or forms of non-mechanical ...
openaire   +2 more sources

A good beginning: study protocol for a group-randomized trial to investigate the effects of sit-to-stand desks on academic performance and sedentary time in primary education

BMC Public Health, 2020
Background Sedentary behavior is associated with health risks and academic under-achievement in children. Still, children spend a large part of their waking hours sitting at a desk at school. Recent short-term studies demonstrated the potential of sit-to-
A. (Lex) E. Q. van Delden, Guido P. H. Band, Joris P. J. Slaets   +2 more
doaj   +1 more source

End-of-life care in the Dutch medical curricula

Perspectives on Medical Education, 2018
Introduction Future doctors must be trained in giving appropriate care to terminal patients. In several countries, medical curricula have been reviewed for the attention devoted to end-of-life care (ELC).
Josefien de Bruin, Mary-Joanne Verhoef, Joris P. J. Slaets, David van Bodegom   +3 more
doaj   +1 more source