Results 61 to 70 of about 189,973 (301)

Impact of physical and mental health on life satisfaction in old age: a population based observational study

open access: yesBMC Geriatrics, 2016
Background It is widely assumed that poor health lowers life satisfaction when ageing. Yet, research suggests this relationship is not straightforward.
Thomas Puvill   +4 more
doaj   +1 more source

The effects of the COVID-19 lockdowns on motor skill development of 6- and 7-year old children in the Netherlands: a longitudinal study

open access: yesBMC Public Health, 2023
Background The closing of schools and sports clubs during the COVID-19 lockdown raised questions about the possible impact on children’s motor skill development.
Anne R. den Uil   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Overzicht meetinstrumenten Urban Vitality - onderzoek naar kwetsbare ouderen: Urban Vitality measurement instruments inventory [PDF]

open access: yes, 2020
A list of measurement instruments used in Urban Vitality research projects regarding frailty and ageing. The list is based on the research protocols of the 14 projects that were examined.
de Jong, A.S.   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Features of multi-fractal structure of high-altitude lightning discharges in the ionosphere: elves, jets, sprites

open access: yesThe Journal of Engineering, 2019
Physical properties of elves, jets and sprites, which are the most interesting types of high-attitude discharges in the atmosphere, are considered in the work. The results of researches of its fractal characteristics are presented.
Alexander A. Potapov, Vitality A. Cerman
doaj   +1 more source

Escape, expand, embrace: the transformational lived experience of rediscovering the self and the other while dancing with Parkinson’s or Multiple Sclerosis

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being, 2023
Purpose The purpose of this study was to explore the lived experience of dancing with Parkinson’s and Multiple Sclerosis in an inclusive dance group called ReDiscoverMe (RDM).
Anna M. Carapellotti   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Vitalism as Pathos [PDF]

open access: yesBiosemiotics, 2016
This paper addresses the remarkable longevity (in spite of numerous 'refutations') of the idea of vitalism in the biological sciences and beyond. If there is to be a renewed vitalism today, however, we need to ask - on what kind of original conception of life should it be based?
openaire   +4 more sources

Fitting of Japanese male vitality curves by gamma vitality model

open access: yes, 2022
Three termed gamma distribution model of vitality, gamma vitality model, is found to fit human vitality curves well. All the life table data which I tried to fit could be well fit by this model. This was the start point of my research.
Toshiharu Kubo (11950814)
core   +1 more source

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