Results 11 to 20 of about 1,446,129 (349)

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Nature, 2022
Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation1, has a key role in organ injury, degenerative disease and vulnerability of therapy-resistant cancers2.
Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, A. Wahida, S. Doll, W. Tonnus, Palina Nepachalovich, E. Eggenhofer, Maceler Aldrovandi, B. Henkelmann, Ken‐ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, R. Feederle, D. Hass, A. Maida, A. Mourão, A. Linkermann, E. Geissler, K. Nakagawa, T. Abe, M. Fedorova, B. Proneth, D. Pratt, M. Conrad   +26 more
semanticscholar   +1 more source

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths

Nutrients, 2020
The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce the risk of infection and death in addition to quarantines are desperately needed.
W. Grant, H. Lahore, S. McDonnell, C. Baggerly, Christine B. French, J. Aliano, H. Bhattoa   +6 more
semanticscholar   +1 more source

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial

British medical journal, 2022
Objective To investigate whether vitamin D and marine derived long chain omega 3 fatty acids reduce autoimmune disease risk. Design Vitamin D and omega 3 trial (VITAL), a nationwide, randomized, double blind, placebo controlled trial with a two-by-two ...
J. Hahn, N. Cook, E. Alexander, S. Friedman, J. Walter, V. Bubes, G. Kotler, I. Lee, J. Manson, K. Costenbader   +9 more
semanticscholar   +1 more source

Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.

Journal of Clinical Endocrinology and Metabolism, 2011
OBJECTIVE The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. PARTICIPANTS The Task Force was composed of a
Michael F. Holick, Neil C. Binkley, H.A. Bischoff-Ferrari, Catherine M. Gordon, David A. Hanley, Robert P. Heaney, M. Murad, Connie M. Weaver   +7 more
semanticscholar   +1 more source

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance The efficacy of vitamin D3 supplementation in coronavirus disease 2019 (COVID-19) remains unclear. Objective To investigate the effect of a single high dose of vitamin D3 on hospital length of stay in patients with COVID-19.
Igor H. Murai, Alan L. Fernandes, L. Sales, A. Pinto, K. Goessler, Camila S C Duran, C. B. R. Silva, A. Franco, M. B. Macêdo, Henrique H H Dalmolin, J. Baggio, G. G. M. Balbi, B. Z. Reis, L. Antonangelo, V. Caparbo, B. Gualano, R. Pereira   +16 more
semanticscholar   +1 more source

The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know

Journal of Clinical Endocrinology and Metabolism, 2010
This article summarizes the new 2011 report on dietary requirements for calcium and vitamin D from the Institute of Medicine (IOM). An IOM Committee charged with determining the population needs for these nutrients in North America conducted a ...
A. Ross, J. Manson, S. Abrams, J. F. Aloia, J. F. Aloia, P. Brannon, S. Clinton, R. Durazo-Arvizu, J. Gallagher, R. Gallo, Glenville Jones, C. Kovacs, S. Mayne, C. Rosen, S. Shapses   +14 more
semanticscholar   +1 more source

Vitamin C—Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination

Nutrients, 2021
Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its physiological role is much larger and encompasses very different processes ranging from facilitation of iron absorption through involvement in hormones and ...
M. Doseděl, Eduard Jirkovský, K. Macáková, L. Krčmová, L. Javorská, J. Pourová, L. Mercolini, F. Remião, L. Nováková, P. Mladěnka, On Behalf Of The Oemonom   +10 more
semanticscholar   +1 more source

Vitamin D deficiency 2.0: an update on the current status worldwide

European Journal of Clinical Nutrition, 2020
Vitamin D testing and the use of vitamin D supplements have increased substantially in recent years. Currently, the role of vitamin D supplementation, and the optimal vitamin D dose and status, is a subject of debate, because large interventional studies
K. Amrein, Mario Scherkl, Magdalena Hoffmann, Stefan Neuwersch-Sommeregger, M. Köstenberger, Adelina Tmava Berisha, G. Martucci, S. Pilz, O. Malle   +8 more
semanticscholar   +1 more source

The health effects of vitamin D supplementation: evidence from human studies

Nature Reviews Endocrinology, 2021
Vitamin D supplementation can prevent and cure nutritional rickets in infants and children. Preclinical and observational data suggest that the vitamin D endocrine system has a wide spectrum of skeletal and extra-skeletal activities.
R. Bouillon, D. Manousaki, C. Rosen, K. Trajanoska, F. Rivadeneira, J. B. Richards   +5 more
semanticscholar   +1 more source

Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E.

Analytical Biochemistry, 1999
A spectrophotometric method has been developed for the quantitative determination of antioxidant capacity. The assay is based on the reduction of Mo(VI) to Mo(V) by the sample analyte and the subsequent formation of a green phosphate/Mo(V) complex at ...
P. Prieto, M. Pineda, M. Aguilar
semanticscholar   +1 more source