Results 191 to 200 of about 2,020,358 (433)

T‐Cell‐Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS‐CoV‐2 Infection

open access: yesAdvanced Science, EarlyView.
This study describes the development of spike‐targeting T‐cell‐dependent bispecific full‐length human immunoglobulin Gs with enhanced efficacy in the treatment of COVID‐19. The significance of T‐cell‐based immunity during infection is highlighted. These results have significant implications for better clinical effectiveness of therapies for COVID‐19 ...
Wenyan Fu   +8 more
wiley   +1 more source

Exergoenvironmental damages assessment in a desert‐based agricultural system: A case study of date production

open access: yesAgronomy Journal, Volume 114, Issue 6, Page 3155-3172, November/December 2022., 2022
Abstract Developing countries, especially those in hot and dry areas, need more attention to achieve sustainable development as they apply excessive inputs in production processes. The present study aims to quantify the amount of environmental emissions and determine the most appropriate pattern of energy use in the date (Phoenix dactylifera L ...
Reza Hesampour   +4 more
wiley   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

open access: yesAdvanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu   +7 more
wiley   +1 more source

Prescription analgesic overuse in older adults: Can we mitigate this growing problem?

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 294-296, December 2022., 2022
With older adults already on numerous prescription medications to manage their chronic conditions, the addition of pain medications could impose an even greater burden due to dependency issues. We need to understand the use of chronic pain medication, especially opioids, discuss current strategies and gaps, and offer potential solutions to mitigate ...
Sara Kakatkar   +2 more
wiley   +1 more source

Vitamin D and calcium metabolism in horses in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Institute of Veterinary, Animal and Biomedical Sciences (IVABS), Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2016
The physiology of vitamin D in horses has not been studied in great depth. Few studies on vitamin D metabolites (25OHD2, 25OHD3, and 1,25(OH)2D) and their relationship to other serum analytes exist. In addition, some studies suggest that equine vitamin D
Azarpeykan, Sara
core  

Oral Microalgae‐Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng   +8 more
wiley   +1 more source

Improving osteoporosis treatment rates in inpatients admitted with hip fracture: A healthcare improvement initiative in a tertiary referral hospital

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 264-271, December 2022., 2022
Our hospital introduced a standardized protocol for the treatment of osteoporosis in patients admitted for hip fracture. The aim of this article was to describe its implementation as well as assess the protocol's effect on treatment rates and safety. In our analysis, there was significant improvement in treatment rates with no instances of acute kidney
Andrew Gan Lin   +5 more
wiley   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

open access: yesAdvanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng   +8 more
wiley   +1 more source

Do smaller chicken farms use more antibiotics? Evidence of antibiotic diffusion from Nigeria

open access: yesAgribusiness, Volume 39, Issue 1, Page 242-262, Winter 2023., 2023
Abstract Farmers across the world have been using antibiotics in poultry production for both therapeutic and nontherapeutic purposes since the mid 1900s. The literature on antibiotic diffusion and intensification is largely focused on developed countries in North America and Western Europe.
Charuta M. Parkhi   +2 more
wiley   +1 more source

The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T Cells

open access: yesAdvanced Science, EarlyView.
RARα is highly expressed by differentiated effector and exhausted T cells and exerts a negative effect on effector T cell differentiation and the associated trafficking receptor switch. Upregulated RARα levels decrease the nuclear histone acetylase (HAT) activity, and this suppresses the expression of key Teff transcription factor BATF and trafficking ...
Patrick Niekamp   +5 more
wiley   +1 more source

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