Results 51 to 60 of about 119,254,893 (314)

Evaluation of Serum Vitamin A, Vitamin E, Cholesterol, and Triglyceride Levels in Pregnant Women Diagnosed with Missed Abortion

İstanbul Medical Journal
Introduction: Missed abortion is defined as the intrauterine death of an embryo or fetus. It occurs when there is no fetal heartbeat, but it does not result in bleeding or miscarriage. It accounts for approximately 15% of all pregnancies.
Ayça Kubat Küçükyurt, Arzu Çetin, Cansel Tanrıkulu   +2 more
doaj   +1 more source

The protective effect of vitamin A on Concor induced structural changes of the liver and kidney in adult rats

Current Issues in Pharmacy and Medical Sciences, 2022
Concor is a beta-blocker drug used to treat high blood pressure, acute coronary syndrome, and to control the rapid pulse of the heart such as atrial fibrillation.
Ahmed Mareb H., Taeel Faten Dhanoon
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A metabolomic investigation of the effects of vitamin E supplementation in humans [PDF]

, 2012
Background Vitamin E is a nutrient with both antioxidant and non-antioxidant activities and has been shown to modulate the function of a number of cell types in vitro and in human studies.
John K Lodge, Max Wong, Lodge John K, Lodge, John, Wong, Max, Wong Max   +5 more
core   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Zein/Phospholipid Composite Nanoparticles for Successful Delivery of Gallic Acid into aHSCs: Influence of Size, Surface Charge, and Vitamin A Coupling

International Journal of Nanomedicine, 2020
Shaimaa Ali Ali Radwan,1 Walaa H El-Maadawy,2 Carol Yousry,1 Aliaa Nabil ElMeshad,1 Raguia Aly Shoukri1 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; 2Department of Pharmacology, Theodor ...
Radwan SAA, El-Maadawy WH, Yousry C, ElMeshad AN, Shoukri RA   +4 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Prevalence and risk factors for vitamin C deficiency in North and South India: A two centre population based study in people aged 60 years and over [PDF]

, 2011
BackgroundStudies from the UK and North America have reported vitamin C deficiency in around 1 in 5 men and 1 in 9 women in low income groups. There are few data on vitamin C deficiency in resource poor countries.ObjectivesTo investigate the prevalence ...
K. Gupta Sanjeev, Maraini Giovanni, Ravilla D. Ravindran, Giovanni Maraini, Ravilla Thulasiraj D., John Neena, Thulasiraj D. Ravilla, John, Neena, Thulasiraj D Ravilla, Young, Ian S., R Jayanthi, S. Young Ian, Usha Chakravarthy, Chakravarthy Usha, Fletcher Astrid E., Young, Ian S, Ravilla D Ravindran, Praveen Vashist, Ravilla, Thulasiraj D, Chakravarthy, Usha, Kathryn E. Fitzpatrick, Fitzpatrick, Kathryn E, Camparini, Monica, Astrid E Fletcher, Gupta, S.K., R. Jayanthi, Maraini, G., John, N., Ravilla, T.D., Fitzpatrick Kathryn E., Fitzpatrick, K.E., Maraini, Giovanni, Camparini, M., Fletcher, Astrid E, Gupta, Sanjeev K, Monica Camparini, Kathryn E Fitzpatrick, Ravindran, Ravilla D, Neena John, Fletcher, A.E., Jayanthi, R, Sanjeev K Gupta, Ravindran, R.D., Vashist Praveen, Sanjeev K. Gupta, Vashist, Praveen, Astrid E. Fletcher, Camparini Monica, Ian S Young, Jayanthi R., Jayanthi, R., Ravindran Ravilla D., Vashist, P., Ian S. Young   +53 more
core   +2 more sources

The Chemistry of Vitamins [PDF]

Science, 1921
There has been a notable revival of interest in the chemistry of vitamins within the past few years. The recent work has led to the isolation of more or less completely crystalline compounds having the properties ascribed to vitamins A, B and D. The evidence now available appears to definitely establish the conclusion that vitamins are not to be ...
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source