Results 141 to 150 of about 821,703 (378)

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

open access: yesGlia, EarlyView.
Multiple sclerosis involves chronic CNS inflammation and neurodegeneration. This review highlights glial cells as key drivers in progressive MS, focusing on lesion pathology, molecular dysfunction, and human‐relevant model systems. ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive ...
Volker Siffrin
wiley   +1 more source

Vitamin B1 in Bacterial Metabolism.

open access: yesExperimental Biology and Medicine, 1938
Since the work of Peters1 showing that the oxidation of pyruvic acid in pigeon-brain requires the presence of vitamin B1, attention has been called to the function of this vitamin in the pyruvate-metabolism of yeast and bacteria. Lohmann and Schuster2 have demonstrated that the co-enzyme of carboxylase, co-carboxylase, is diphosphorylated vitamin B1 ...
M. Silverman, C. H. Werkman
openaire   +2 more sources

Vitamin E supplementation prevents obesogenic diet-induced developmental abnormalities in SR-B1 deficient embryos

open access: yesFrontiers in Cell and Developmental Biology
IntroductionGenetic and environmental factors influence the risk of neural tube defects (NTD), congenital malformations characterized by abnormal brain and spine formation.
Alonso Quiroz   +5 more
doaj   +1 more source

The Effect of Vitamin B1 Application on The Growth of Cocoa Seedlings [PDF]

open access: yes
Vitamin B1 is a vitamin that has a very important role for plants. The application of vitamin B1 (thiamin) is expected to increase plant growth, including in the seedling phase.
Harahap, Fitri Sauda, Novalina, Novalina
core   +1 more source

Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation

open access: yesiMeta, EarlyView.
Multi‐omics sequencing and correlation analysis identified the beneficial role of Faecalibacterium prausnitzii (F. prausnitzii)‐derived butyric acid (BA) as a key metabolite in the restoration of valve function in calcific aortic valve disease (CAVD). The therapeutic efficacy of BA in attenuating CAVD progression was confirmed in vitro, ex vivo, and in
Chunli Wang   +18 more
wiley   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang   +12 more
wiley   +1 more source

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