Results 101 to 110 of about 78,306 (357)

Diagnosis of Vitamin B12 Deficiency

International Journal of Clinical Therapeutics and Diagnosis, 2013
Vitamin B12 (cobalamin) deficiency occurs primarily as a result  of insufficient dietary intake or poor absorp-tion. There is widespread global prevalence of vitamin B12 deficiency, resulting in considerable morbidity.
openaire   +2 more sources

B12‐Cofactor Inactivation by Cobalt to Rhodium Mutation in Methylrhodibalamin: An Antivitamin B12 and Antibiotic

ChemistryEurope, EarlyView.
Replacement of cobalt in the organometallic B12‐cofactor methylcobalamin (MeCbl) by rhodium furnishes a structural mimic with a significantly stronger metal–carbon bond. This synthetically challenging formal metal‐mutation converts the naturally optimized biological methyl‐transfer catalyst MeCbl into a designed antivitamin B12, an inactivated B12 ...
Florian J. Widner, Klaus Wurst, Markus Ruetz, Christoph Kieninger, Christoph Kreutz, Michael D. Paxhia, Evelyne Deery, Martin J. Warren, Bernhard Kräutler   +8 more
wiley   +1 more source

Is it time to revisit vitamin B12 for mental health and cognitive functions in elderly? [PDF]

, 2018
Decline in cognitive and motor functions and in mental health are commonly seen with aging. Although many reports attribute their etiology to aging, these conditions may have vitamin B12 deficiency as an underlying mechanism.
Begdache, Lina, Marhaba, Rani
core   +1 more source

Neurological disorders in vitamin B12 deficiency

Terapevticheskii arkhiv, 2019
The review discusses thesteps of vitamin B12 metabolism and its role in maintaining of neurological functions. The term "vitamin B12 (cobalamin)" refers to several substances (cobalamins) of a very similar structure. Cobalamin enters the body with animal products.
Ch S Pavlov, I V Damulin, Yu. O. Shulpekova, E A Andreev   +3 more
openaire   +4 more sources

Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment

Clinical Pharmacology &Therapeutics, EarlyView.
Pemetrexed is a cornerstone in chemo(immunotherapy) of non‐small cell lung cancer and mesothelioma; however, it is contraindicated in patients with renal impairment due to severe toxicity concerns. Therefore, a large proportion of patients is withheld from effective chemo(immunotherapy).
Nikki de Rouw, Leila‐Sophie Otten, Mart P. Kicken, Berber Piet, Bonne Biesma, Bianca van Veggel, Christi M.J. Steendam, Ben van den Borne, Lizza E.L. Hendriks, Sander Croes, Anne‐Marie C. Dingemans, Daphne W. Dumoulin, Ron H.J. Mathijssen, Jacobus A. Burgers, Alwin D.R. Huitema, Hieronymus J. Derijks, Maarten J. Deenen, Michel M. van den Heuvel, Rob ter Heine   +18 more
wiley   +1 more source

N‐terminal pro‐brain natriuretic peptide and cardiorenal outcome in patients with anaemia in chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 848-858, April 2025.
Abstract Aims Blood levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) may be modified by low renal clearance and anaemia. The aim of this study was to investigate the impact of the blood NT‐proBNP level on cardiovascular and renal outcomes in patients with these two manifestations.
Hiroshi Nishi, Masaomi Nangaku, Tadashi Sofue, Tatsuo Kagimura, Ichiei Narita   +4 more
wiley   +1 more source

Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B12-deficient rats [PDF]

, 2009
Folate is generally considered as a safe water-soluble vitamin for supplementation. However, we do not have enough information to confirm the potential effects and safety of folate supplementation and the interaction with vitamin B12 deficiency.
Achón, Achón, Araki, Baik, Bailey, Boutell, Cooper, Cullen, Fei, Finkelstein, Giorgio, Goodwin, Hyesun Min, Jones, Jones, Kim, Kim, Kuhn, Kutzbach, Lachance, Ludwig, Pogribny, Selhub, Seshadri, Sohn, Stabler, Tamura, Ubbink, Wagner, White   +29 more
core   +2 more sources

Food Toxicology and Safety: Evaluating Dietary Risks and Functional Ingredients

Food Bioengineering, EarlyView.
The pyramid's foundation reminds us that true health begins with daily habits—engage in 30–60 min of physical activity, nurture social connections and secure 7–9 h of restorative sleep each night to support metabolism, mood regulation, and hormonal balance—while continuously hydrating with 8–12 glasses of water and unsweetened herbal infusions (green ...
Sujaritha Jayaraj, Lavanya Kothandan, Vijay Babu Murugan, Saravana Kumar Prakash, Vandhana Vijayakumar, Elizabeth Rani   +5 more
wiley   +1 more source

Vitamin B12 deficiency results in severe oxidative stress, leading to memory retention impairment in Caenorhabditis elegans

Redox Biology, 2017
Oxidative stress is implicated in various human diseases and conditions, such as a neurodegeneration, which is the major symptom of vitamin B12 deficiency, although the underlying disease mechanisms associated with vitamin B12 deficiency are poorly ...
Tomohiro Bito, Taihei Misaki, Yukinori Yabuta, Takahiro Ishikawa, Tsuyoshi Kawano, Fumio Watanabe   +5 more
doaj  

Microwave Assisted Fluidized Bed Spray Soaking and Gelatinization for Whole Grain Rice Fortification

Food Frontiers, EarlyView.
Spray soaking of micronutrient solution (0.106 mg/ml) with the pre‐optimized processing condition resulted in a gain in iron content (21.25 mg of iron/kg), non‐significantly impacting its quality. ABSTRACT Extruded fortified rice kernel often differs in its physicochemical, soaking, and cooking properties from regular rice and is not preferred due to ...
Ankanksha Kumari, Bijendra Sahoo, Shubhajit Sarkhel, Soumili Hait, Rajeshwari Chatterjee, Anand Mohan, Anupam Roy   +6 more
wiley   +1 more source