Results 31 to 40 of about 746,629 (279)

The Many Faces of Cobalamin (Vitamin B12) Deficiency

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019
Although cobalamin (vitamin B12) deficiency was described over a century ago, it is still difficult to establish the correct diagnosis and prescribe the right treatment.
Bruce H.R. Wolffenbuttel, MD, PhD, Hanneke J.C.M. Wouters, BSc, M. Rebecca Heiner-Fokkema, PhD, Melanie M. van der Klauw, MD, PhD   +3 more
doaj   +1 more source

Vitamin B-12 deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid [PDF]

, 2009
The risk of nutrient deficiencies increases with age in our modern Western society, and vitamin B(12) deficiency is especially prevalent in the elderly and causes increased homocysteine (Hcy) and methylmalonic acid (MMA) levels.
Bravenboer, N., Vaes, Bart L T, Vaes, B.L.T., Everts, V., Wilma T. Steegenga, Bravenboer, Nathalie, Steegenga, W.T., Lute, Carolien, Carolien Lute, de Groot, L.C.P.G.M., Müller, M.R., Henk J. Blom, de Groot, C.P.G.M., Muller, M., Dhonukshe-Rutten, R.A.M., de Groot, Lisette C P G M, Dhonukshe-Rutten, R.A., Bart L. T. Vaes, Teun J. de Vries, Blom, Henk J, Nathalie Bravenboer, Groot, L.C.P.G.M. de, de Vries, Teun J, Müller, Michael, Everts, Vincent, Rosalie A. Dhonukshe-Rutten, Michael Müller, de Vries, T.J., Lisette C. P. G. M. de Groot, Dhonukshe-Rutten, Rosalie A, Steegenga, Wilma T, Groot, C.P.G.M., de, Lute, C., Vries, T. J., Blom, H.J., Everts, V, Vries, T.J., de, Vincent Everts   +37 more
core   +2 more sources

Prevalence of vitamin B12 insufficiency during pregnancy and its effect on offspring birthweight: a systematic review and meta-analysis. [PDF]

, 2016
Background: Vitamin B-12 and folate are micronutrients essential for normal embryogenesis. Vitamin B-12 insufficiency in pregnancy is high in certain parts of the world, such as India, and although this has been linked to low birth weight (LBW) in these ...
Rafnsson, Snorri B., Kandala, Ngianga-Bakwin, Saravanan, Ponnusamy, Yajnik, Chittaranjan, Sukumar, Nithya, Rafnsson, Snorri B, Bhopal, Raj, Yajnik, Chittaranjan S., Rafnsson, Snorri, Yajnik, Chittaranjan S   +9 more
core   +1 more source

Vitamin B12 deficiency

The Professional Medical Journal, 2018
Objectives: To determine the frequency of vitamin B12 deficiency in patientswith hypothyroidism. Study Design: Cross sectional descriptive study. Period: 12-05-2016to 11-11-2016. Setting: Liaquat University Hospital Jamshoro / Hyderabad. Patients andMethods: All the patients of known hypothyroid patients for ≥01month duration, 20-50 yearsof age, either
Daniel Bell, Rohit Sharma, Mohamed Saber
  +6 more sources

Subacute combined degeneration of the spinal cord in functional vitamin B12 deficiency states

Advances in Clinical Neuroscience & Rehabilitation, 2021
Vitamin B12 is an essential enzymatic cofactor in multiple cellular metabolic pathways. Deficiency states can arise as a result of both depletion of absolute systemic levels and pathological processes that block its ability to act as an enzymatic ...
Christina Englezou, Di Liang
doaj   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Persistent diarrhea, hemolytic anemia, and splenohepatomegaly due to Vitamin B12 deficiency in an infant

Journal of Applied Hematology, 2018
Vitamin B12 is essential for DNA and RNA synthesis. Vitamin B12 deficiency usually occurs in infants who are exclusively breastfed born to Vitamin B12-deficient mothers.
K Jagadish Kumar, Srineha Prudhvi, Korrayi Balaji, R Rahul   +3 more
doaj   +1 more source

Vitamin B12 Deficiency and Dementia

International Psychogeriatrics, 1995
We set out to investigate the possible beneficial effects on cognitive function of demented patients with cobalamin deficiency after cobalamin replacement. A total of 181 consecutive, demented (DSM-III or DSM-III-R criteria and score below 24 on the Mini-Mental State Examination [MMSE]) outpatients (mean age 77.5 years) were prospectively evaluated and
U G, Cunha, F L, Rocha, J M, Peixoto, M F, Motta, M T, Barbosa   +4 more
openaire   +2 more sources

Involuntary movement in infants during vitamin B12 treatment

Turkish Journal of Hematology, 2011
Megaloblastic anemia is rare in infants and is generally due to vitamin B12 (cobalamin) deficiency in the mother. Neurologic symptoms of vitamin B12 deficiency include irritability, failure to thrive, hypotonia, and developmental regression/delay. Herein
Ayşe Tosun, Yusuf Ziya Aral, Emre Çeçen, Ayvaz Aydoğdu, Bilin Çetinkaya Çakmak   +4 more
doaj   +3 more sources

Should we follow the guidelines on vitamin B12 deficiency and diabetes? A retrospective analysis of data from middle eastern population

Alexandria Journal of Medicine, 2023
Background Vitamin B12 is a micronutrient required for hematopoietic, neuro-cognitive and cardiovascular function. Biochemical and clinical vitamin B12 deficiency has been recognized in patients with type 2 diabetes mellitus.
Ahmed Kamal Swidan, Marwa Ahmed Salah Ahmed   +1 more
doaj   +1 more source