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Vitamin B12 Deficiency [PDF]

, 2020
Vitamin B12 (cobalamin) deficiency and its related hematological and neurological manifestations, of which pernicious and megaloblastic anemia are the most recognized entities, have puzzled the medical community for over a century. These conditions are described in all ages, race and ethnicities, continents, and socioeconomic groups.
Jennifer Davila, Maria C. Velez-Yanguas
openaire   +2 more sources

Profiling immuno-metabolic mediators of vitamin B12 deficiency among metformin-treated type 2 diabetic patients in Ghana.

PLoS ONE, 2021
BackgroundThe association between prolong metformin usage and B12 deficiency has been documented. However, the prevalence estimates of metformin-induced vitamin B12 deficiency showed substantial disparity among studies due to varied study definitions of ...
Samuel Asamoah Sakyi, Edwin Ferguson Laing, Richard Mantey, Alexander Kwarteng, Eddie-Williams Owiredu, Richard Ephraim Dadzie, Benjamin Amoani, Stephen Opoku, Bright Oppong Afranie, Daniel Boakye   +9 more
doaj   +1 more source

Functional vitamin B12 deficiency

Practical Neurology, 2009
We describe a case of functional vitamin B12 deficiency where the repeated measurement of a serum B12 level within the normal range led to delay in the diagnosis of subacute combined degeneration of the spinal cord, and possibly permanent neurological damage as a result.
Turner, M, Talbot, K
openaire   +3 more sources

Vitamin B12 deficiency is associated with adverse lipid profile in Europeans and Indians with type 2 diabetes [PDF]

, 2014
Background: Metformin, a standard therapy in type 2 diabetes, reduces vitamin B12 levels. Studies linking low vitamin B12 levels and cardiovascular disease are equivocal and suggest improving B12 levels may help in primary prevention.
Anjana, RM, Saravanan, P, Jayashri, R., Venkataraman, H., Gokulakrishnan, K, Saravanan, Ponnusamy, Pradeepa, R., Venkataraman, Hema, Venkataraman, H, Sukumar, Nithya, Gokulakrishnan, Kuppan, Adaikalakoteswari, A., Saravanan, P., McTernan, P.G, Pradeepa, Rajendra, McTernan, PG, Sukumar, N, Patel, V., Anjana, R.M, Jayashri, Ramamurthy, Tripathi, G, Pradeepa, R, Kumar, S., Tripathi, G., Kumar, S,, Adaikalakoteswari, A, Mohan, V, Anjana, R., Anjana, Ranjit, Sukumar, N., Jayashri, R, Mohan, Viswanathan, Tripathi, Gyanendra, Kumar, Sudhesh, Antonysunil, Adaikalakoteswari, McTernan, P. G., Patel, V, Kumar, S, McTernan, P.G., Mohan, V., Patel, Vinod, Gokulakrishnan, K.   +41 more
core   +1 more source

Gluten-Free Products Are Insufficient Source of Folate and Vitamin B12 for Coeliac Patients [PDF]

, 2011
Bezglutenska prehrana, jedini lijek za oboljele od celijakije, može biti neuravnotežena zbog nedostataka nekih hranjivih tvari. Bezglutenski proizvodi sadrže manju količinu vitamina B, osobito folata, nego slični proizvodi koji sadrže gluten.
Panjkota Krbavčić, Ines, Colić Barić, Irena, Bituh, Martina, Martina Bituh, Zadro, Zvonko, Žižić, Vesna, Vesna Žižić, Zvonko Zadro, Irena Colić Barić, Ines Panjkota Krbavčić   +9 more
core   +1 more source

Micronutrient malnutrition and wasting in adults with pulmonary tuberculosis with and without HIV co-infection in Malawi. [PDF]

, 2004
BACKGROUND: Wasting and micronutrient malnutrition have not been well characterized in adults with pulmonary tuberculosis. We hypothesized that micronutrient malnutrition is associated with wasting and higher plasma human immunodeficiency virus (HIV ...
Johnny J Kumwenda, Tamara D Clark, Richard D Semba, Harries Anthony D, Zijlstra, Ed E, Clark Tamara D, Taha Taha E, Taha, Taha E, Kumwenda, Johnny J, Semba Richard D, Anthony D Harries, Kumwenda Johnny J, Zijlstra Ed E, Harries, Anthony D, Monique van Lettow, Taha E Taha, Clark, Tamara D, van Lettow Monique, van Lettow, Monique, Ed E Zijlstra, Semba, Richard D   +20 more
core   +2 more sources

High incidence of low vitamin B12 levels in Estonian newborns

Molecular Genetics and Metabolism Reports, 2018
Vitamin B12 deficiency seems to be more common worldwide than previously thought. However, only a few reports based on data from newborn screening (NBS) programs have drawn attention to that subject.
Karit Reinson, Kadi Künnapas, Annika Kriisa, Mari-Anne Vals, Kai Muru, Katrin Õunap   +5 more
doaj   +1 more source

Vitamin B12 deficiency in a large cohort of healthcare professionals across the network of an eyecare organization in India

Indian Journal of Ophthalmology, 2022
Purpose: To evaluate Vitamin B12 levels in healthcare professionals at a tertiary eyecare centre in India. Methods: This was a cross-sectional study conducted among healthcare professionals working at a tertiary eyecare centre in India.
Sushma Nandyala, Ashik Mohamed, Archana Bhargava, Sunita Chaurasia, Sirisha Senthil, Pravin K Vaddavalli   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The association between medication use and vitamin B12 deficiency in the elderly population: a cross- sectional study

BMC Geriatrics
Background Vitamin B12 deficiency is common in the elderly population and can cause severe complications. The use of certain medication has in previous studies been associated with vitamin B12 deficiency in the general population.
Monique P. H. Tillemans, Thijs J. Giezen, Toine C. G. Egberts, Kees J. Kalisvaart   +3 more
doaj   +1 more source