Results 81 to 90 of about 78,306 (357)

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Vitamin B12 deficiency may play an etiological role in atrophic glossitis and its grading: A clinical case-control study

BMC Oral Health, 2022
Background Existing studies have reported the significant association between atrophic glossitis (AG) and hematinic deficiencies, including iron, folate and vitamin B12 deficiency. However, these findings were inconsistent. AG can be graded as partial or
Guan-Ying Chen, Zhi-Qun Tang, Zhe-Xuan Bao   +2 more
doaj   +1 more source

Cistanche tubulosa improves peripheral neuropathy in MPTP‐induced PD mice based on regulation of m6A methylation

Animal Models and Experimental Medicine, EarlyView.
At steady state, DRG ensures low‐level expression of TH+ neurons under the protection of AKT. However, the DRG level of PD mouse model under MPTP toxicity increased significantly, and the expression of IL‐6 and CASP3 increased. This process was accompanied by the occurrence of m6A demethylation, with a significant increase in FTO as the main ...
Yatan Li, Wei Jia, Junhua Hu, Borui Zhang, Xinxin Qi, Jianhua Yang, Xinling Yang   +6 more
wiley   +1 more source

High vitamin B12 level [PDF]

, 2013
Vitamin B12/cobalamin functions as an important co-enzyme in the human body and is essential forpurine and pyrimidine synthesis. Vitamin B12 deficiency is a very well recognized clinical entity but the conditions leading to elevated levels of vitamin B12
Nistala, Puja
core  

Metformin and Vitamin B12 Deficiency: Where Do We Stand? [PDF]

, 2016
The association between metformin use and low vitamin B12 levels in type 2 diabetes mellitus patients is well-established. However, many aspects of the topic remain to be elucidated.
Ahmed, Marwan Awad
core   +2 more sources

Developing HaloTag and SNAP‐Tag Chemical Inducers of Dimerization to Probe Receptor Oligomerization and Downstream Signaling

Angewandte Chemie International Edition, Accepted Article.
Controlling protein‐protein interactions is critical for dissecting signaling pathways, especially those initiated by ligand‐receptor interactions which alter receptor oligomerization and drive downstream signaling cascades. Traditional methods for driving protein‐protein complexes are using antibodies that face limitations in terms of stoichiometry ...
Johannes Broichhagen, Michael Trumpp, Blaise Gatin-Fraudet, Kjell Bruckmann, Wiktor Burdzinski, Kilian Roßmann, Joshua Levitz, Petra Knaus, Jerome Jatzlau   +8 more
wiley   +1 more source

The importance of holotranscobalamin measurement [PDF]

Journal of Medical Biochemistry, 2007
Clinically significant vitamin B12 deficiency can occur even with total vitamin B12 levels apparently within normal range. There is an indeterminate zone between approximately 154 and 300 pmol/L of vitamin B12 where there is likely misclassification of ...
Čabarkapa Velibor, Stošić Zoran, Žeravica Radmila, Ilinčić Branislava, Filipović Ana   +4 more
doaj  

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

An update on vitamin B12-related gene polymorphisms and B12 status. [PDF]

, 2018
Vitamin B12 is an essential micronutrient in humans needed for health maintenance. Deficiency of vitamin B12 has been linked to dietary, environmental and genetic factors. Evidence for the genetic basis of vitamin B12 status is poorly understood. However,
A Adaikalakoteswari, A Adaikalakoteswari, A Barnabe, A Hazra, A Hazra, A McCaddon, A Shiran, A Stanislawska-Sachadyn, A Tamura, A. Adaikalakoteswari, AA Seyerle, AB Hall, AC Alessio, AC Alessio, B Annibale, B Fowler, B Franke, B Schwahn, B Seetharam, BH Thuesen, BM Riedel, BS Sheu, C Chery, CJ Boushey, D Coelho, D Hu, DJ Smyth, E De Mattia, E Lahner, EL Kurnat-Thoma, EV Quadros, EV Quadros, F Cobayashi, F Keyfi, F Namour, F Pangilinan, F Zhao, FM Faraci, G Lauc, HJ Porck, HS Lee, I. A. Shatwaan, J Al-Tahan, J Johnston, J Johnston, J Kim, J Kumar, J Li, J Serpa, J Wang, J Wuerges, J. A. Lovegrove, JC Deme, JC Fyfe, JF Arendt, JF Arendt, JK Goodrich, JL Donato, JL Kutok, JP Lerner-Ellis, JW Zinck, K Kaptan, K Lechner, K. S. Vimaleswaran, KA Roecklein, KM von Castel-Dunwoody, KR Dholakia, L Strittmatter, L Strittmatter, L Zhao, M Aminoff, M Azevedo, M Drogemuller, M Soejima, M Tong, MG Garrod, MG van Oijen, N Grarup, N Kato, N Korotkova, N Sukumar, P Haggarty, P Haggarty, P Wacklin, P. Saravanan, R Castro, R Kozyraki, S Brustolin, S Henry, S Hustad, S Shahab-Ferdows, S. Surendran, SE Nilsson, SK Moestrup, SP Stabler, SP Yip, T Andrew, T Kudo, T Takahashi-Iñiguez, T Tanaka, TB Shows, V Fettelschoss, VS Tanwar, WS Bush, X Li, X Lin, Y Goto   +106 more
core   +2 more sources

High-folate-low-vitamin B12 interaction syndrome

European Journal of Case Reports in Internal Medicine
Introduction: Vitamin B12 deficiency is characterised by haematological and neurological complications, from mild symptoms (e.g. fatigue and paraesthesia), to severe symptoms (e.g. pancytopenia and combined degeneration of the spinal cord).
Claudia Cicchini, Antonio De Magistris, Alberto Del Sasso, Donatella Livoli, Francesco Rocco Pugliese   +4 more
doaj   +1 more source