Results 281 to 290 of about 900,461 (349)

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

open access: yesAdvanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song   +9 more
wiley   +1 more source

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

open access: yesAdvanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang   +7 more
wiley   +1 more source

Does Contract Farming Improve Diet Quality? The Case of Senegalese Smallholders

open access: yesAgribusiness, EarlyView.
ABSTRACT The institution of contract farming has gained prominence in most developing countries owing to its numerous benefits. While several studies have already highlighted the welfare benefits of contract farming, very few have investigated the effects on diet quality, despite poor quality diets being a serious challenge in most parts of the ...
Francis E. Ndip, Takeshi Sakurai
wiley   +1 more source

The Impacts of Health and Environmental Information Nudges on Meat Choices: Where Does Goat Meat Fit?

open access: yesAgribusiness, EarlyView.
ABSTRACT Amidst a recent surge in US goat meat imports to meet growing demand, this study contributes to the meat demand literature by examining consumer preferences for goat meat, a relatively healthy and environmentally friendly alternative to other popular meats.
Binod Khanal   +2 more
wiley   +1 more source

Aggregation‐Enhanced Asymmetric Heptamethine Cyanine Nanoplatform for Imaging‐Guided Synergistic Phototherapy and Ferroptosis

open access: yesAggregate, EarlyView.
An asymmetric heptamethine cyanine photosensitizer, Cyp‐TPE, is designed to break molecular symmetry and form ordered nanoaggregates, resulting in ultrahigh ROS generation and synergistic photothermal/photodynamic activity. It further triggers ferroptosis and lysosomal dysfunction, providing a potent aggregate‐based theranostic platform for imaging ...
Mengyuan Cui   +6 more
wiley   +1 more source

A Dual‐Ion Multiphysics Model for Smart and Sustainable Sensors Based on Bacterial Cellulose

open access: yesAdvanced Intelligent Systems, EarlyView.
Bacterial cellulose (BC), functionalized with ionic liquids (ILs) and conductive polymers, offers promise for sustainable sensor applications. To enable real‐world integration, this work presents the first dual‐carrier, multiphysics white‐box model of mechanoelectric transduction in BC–IL sensors, combining mechanical deformation and ion transport ...
Francesca Sapuppo   +7 more
wiley   +1 more source

Variants in AKR1D1 and Infant Mortality: Should Bile Acid Screening be a Routine Part of Newborn Screening?

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson   +3 more
wiley   +1 more source

Targeted Medical Therapies for Vascular Anomalies: A Clinical Review

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Vascular anomalies represent a broad spectrum of disorders characterized by aberrant blood or lymphatic vessel development, which can lead to complex clinical phenotypes. Historically, vascular anomalies were classified solely on the basis of their clinical and histopathologic features.
Whitney Eng
wiley   +1 more source

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