Results 311 to 320 of about 863,295 (352)
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The production of antibodies to vitamin B-12
Clinica Chimica Acta, 1979The conjugation of vitamin B-12 to HSA by means of a combined ethylcarbodiimide N-hydroxysuccinimide conjugation method at pH 5.5 is described. It gave a ratio of 2.7 mol vitamin B-12/mol HSA. Five rabbits were immunized with this conjugate emulsified in Freund's complete adjuvant. After one booster injection high titre antisera (1 : 450 000--1 : 1 500
S.Stefan Ahrenstedt, Jan I. Thorell
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BMJ, 2010
An 85 year old man had a preoperative assessment for a knee replacement. His full blood count was normal apart from haemoglobin 95 g/l and mean corpuscular volume 105 fl. He drank no alcohol. Further testing showed that his vitamin B-12 was low: 90 pmol/l (reference range 160-800 pmol/l).
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An 85 year old man had a preoperative assessment for a knee replacement. His full blood count was normal apart from haemoglobin 95 g/l and mean corpuscular volume 105 fl. He drank no alcohol. Further testing showed that his vitamin B-12 was low: 90 pmol/l (reference range 160-800 pmol/l).
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Serial measurements of vitamin B-12 and vitamin B-12-binding capacity in marasmic kwashiorkor
Clinica Chimica Acta, 1975Vitamin B-12 and total vitamin B-12-binding capacity (TBBC) have been determined by a radio-saturation assay in the blood of a large group of patients suffering from marasmic kwashiorkor on admission, and during their whole re-feeding. The results have been compared with values obtained in control children of the same ethnic group and with normal ...
Lejeune-Lenain, C., Fondu, Pierre
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Annals of Nutrition and Metabolism, 2012
The discovery of vitamin B<sub>12</sub>, the elucidation of its role in metabolism, and the effects and treatment of its deficiency occurred in distinct phases over more than 100 years, and it was the subject of two separate Nobel Prizes. The valuable contribution of clinical reports and studies of patients with pernicious anemia throughout
John M. Scott, Anne M. Molloy
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The discovery of vitamin B<sub>12</sub>, the elucidation of its role in metabolism, and the effects and treatment of its deficiency occurred in distinct phases over more than 100 years, and it was the subject of two separate Nobel Prizes. The valuable contribution of clinical reports and studies of patients with pernicious anemia throughout
John M. Scott, Anne M. Molloy
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Biosynthesis of vitamin B-12 Part I. Role of the ribosomal proteins in vitamin B-12 biosynthesis
Biochimica et Biophysica Acta (BBA) - General Subjects, 19811. 70 S ribosomes isolated from strains of Escherichia coli 113-3, K12 and B take part in vitamin B-12 biosynthesis from AdoCbi-GDP, NAD and dimethylbenzimidazole in the presence of enzymes of the cytosol fraction. 2. 70 S ribosomes from E.coli 113-3 bind Ado[58Co]Cbi-GDP. This reaction is independent of fusidic acid. 3.
E. Pezacka, W. Walerych
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Vitamin B, 12 Deficiency in the Elderly
Clinics in Geriatric Medicine, 1985Vitamin B 12 deficiency is usually a disease of older persons, and much controversy has surrounded the significance of the deficiency of this vitamin in these patients. This article explores the mechanism of action of vitamin B 12, the clinical and laboratory features of vitamin B 12 deficiency, and a rational treatment plan.
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The Production of Vitamin B 12 in the Horse
British Veterinary Journal, 1971SUMMARY The concentration of vitamin B 12 in the contents of the alimentary tract of the horse was found to increase from stomach to rectum. Micro-organisms which produced vitamin B 12 in the different regions of the tract were isolated and identified as far as possible.
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Vitamin B-12 status in a macrobiotic community
The American Journal of Clinical Nutrition, 1991Vitamin B-12 status was assessed in a group of 110 adults and 42 children from a macrobiotic community in New England. Dietary and anthropometric information also was obtained. Fifty-one percent of the adults had low concentrations of serum vitamin B-12, which inversely correlated with duration of macrobiotic diet practice.
D R Miller +3 more
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Science, 1971
In spite of the considerable progress made in recent years toward the understanding of the chemistry and biological function of the cobalt-containing B 12 group of compounds, much of the information still is more descriptive than definitive in nature.
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In spite of the considerable progress made in recent years toward the understanding of the chemistry and biological function of the cobalt-containing B 12 group of compounds, much of the information still is more descriptive than definitive in nature.
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A column radioassay for the quantification of vitamin B-12
Clinica Chimica Acta, 1975A rapid and convenient column radioassay for the quantification of vitamin B-12 in clinical specimens has been developed. A mixture of the specimen and radiolabeled B-12 was applied to a column containing immobilized intrinsic factor and allowed to incubate for two hours. A buffer wash then separated bound and free B-12.
R.C. Boguslaski, C.P. Rathjen
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