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The Role of Chalcogen Bonding in Organic Dichalcogenides of Biological Interest
Chemistry – An Asian Journal, EarlyView.Experimental and theoretical studies consistently show that selenium and tellurium in dichalcogenides compounds can function as efficient chalcogen bond (ChB) donors. Their electrophilic behavior may suggest that the formation of a ChB could represent the preliminary step of the molecular mechanism resulting in the anti‐redox activity of ...
Abhishek Tripathi +9 more
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Biotechnology and Applied Biochemistry, EarlyView.Abstract Over the past 10 years, nanotechnology has emerged as a very promising technique for a wide range of biomedical applications. Green synthesized metal and metal oxide nanoparticles (NPs) are cheap, easy to produce in large quantities, and safe for the environment.
Kaan Şendal +6 more
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Preparation of vitamin B-12-free serum for the use in vitamin B-12 radioassays
Clinica Chimica Acta, 1979In radioassays for serum vitamin B-12, the separation of free and bound vitamin is usually made with charcoal absorption. The specificity of this separation depends on the amount of charcoal and the protein content and constitution of the medium. The large difference in protein concentration between the samples for the dilution curve and the serum ...
J. Van Kapel, J. Abels, Jan Lindemans
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The production of antibodies to vitamin B-12
Clinica Chimica Acta, 1979The conjugation of vitamin B-12 to HSA by means of a combined ethylcarbodiimide N-hydroxysuccinimide conjugation method at pH 5.5 is described. It gave a ratio of 2.7 mol vitamin B-12/mol HSA. Five rabbits were immunized with this conjugate emulsified in Freund's complete adjuvant. After one booster injection high titre antisera (1 : 450 000--1 : 1 500
S.Stefan Ahrenstedt, Jan I. Thorell
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BMJ, 2010
An 85 year old man had a preoperative assessment for a knee replacement. His full blood count was normal apart from haemoglobin 95 g/l and mean corpuscular volume 105 fl. He drank no alcohol. Further testing showed that his vitamin B-12 was low: 90 pmol/l (reference range 160-800 pmol/l).
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An 85 year old man had a preoperative assessment for a knee replacement. His full blood count was normal apart from haemoglobin 95 g/l and mean corpuscular volume 105 fl. He drank no alcohol. Further testing showed that his vitamin B-12 was low: 90 pmol/l (reference range 160-800 pmol/l).
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Serial measurements of vitamin B-12 and vitamin B-12-binding capacity in marasmic kwashiorkor
Clinica Chimica Acta, 1975Vitamin B-12 and total vitamin B-12-binding capacity (TBBC) have been determined by a radio-saturation assay in the blood of a large group of patients suffering from marasmic kwashiorkor on admission, and during their whole re-feeding. The results have been compared with values obtained in control children of the same ethnic group and with normal ...
Lejeune-Lenain, C., Fondu, Pierre
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Annals of Nutrition and Metabolism, 2012
The discovery of vitamin B<sub>12</sub>, the elucidation of its role in metabolism, and the effects and treatment of its deficiency occurred in distinct phases over more than 100 years, and it was the subject of two separate Nobel Prizes. The valuable contribution of clinical reports and studies of patients with pernicious anemia throughout
John M. Scott, Anne M. Molloy
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The discovery of vitamin B<sub>12</sub>, the elucidation of its role in metabolism, and the effects and treatment of its deficiency occurred in distinct phases over more than 100 years, and it was the subject of two separate Nobel Prizes. The valuable contribution of clinical reports and studies of patients with pernicious anemia throughout
John M. Scott, Anne M. Molloy
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Biosynthesis of vitamin B-12 Part I. Role of the ribosomal proteins in vitamin B-12 biosynthesis
Biochimica et Biophysica Acta (BBA) - General Subjects, 19811. 70 S ribosomes isolated from strains of Escherichia coli 113-3, K12 and B take part in vitamin B-12 biosynthesis from AdoCbi-GDP, NAD and dimethylbenzimidazole in the presence of enzymes of the cytosol fraction. 2. 70 S ribosomes from E.coli 113-3 bind Ado[58Co]Cbi-GDP. This reaction is independent of fusidic acid. 3.
E. Pezacka, W. Walerych
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