Results 121 to 130 of about 340,270 (377)

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency. [PDF]

Cureus, 2022
Abdalla E, Al-Sadi A, Fadul A, Ahmed AH, Musa M.   +4 more
europepmc   +1 more source

Megaloblastic anaemia in vitamin B₁₂deficiency [PDF]

British Journal of Nutrition, 2003
In rats, in contrast with human subjects who develop megaloblastic anaemia due to vitamin B 12 deficiency, haematological abnormalities with anaemia were not observed under normoxic conditions even though plasma vitamin B 12 concentration was reduced to < 15 % of a normal concentration by depleting dietary vitamin B 12 .
openaire   +3 more sources

Estimating the avoidable burden of certain modifiable risk factors in osteoporotic hip fracture using Generalized Impact Fraction (GIF) model in Iran [PDF]

, 2013
Backgrounds: The number of hip fractures, the most common complication of osteoporosis, has increased rapidly over the past decades. The goal of this study is to estimate the avoidable burden of certain modifiable risk factor of the condition using the ...
Aghamaleki, A., Dini, M., Keshtkar, A., Khashayar, P., Larijani, B., Mansour, A., Matin, B., Saghafi, S., Shahnazari, B., Soltani, A.   +9 more
core   +1 more source

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

Advanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim, Giheon Ha, Minseok Kim, Minjin Kwak, Han‐Jun Kim, Junmin Lee   +5 more
wiley   +1 more source

High vitamin B₁₂ level and good treatment outcome may be associated in major depressive disorder

BMC Psychiatry, 2003
Background Despite of an increasing body of research the associations between vitamin B12 and folate levels and the treatment outcome in depressive disorders are still unsolved. We therefore conducted this naturalistic prospective follow-up study.
Tanskanen Antti, Tolmunen Tommi, Hintikka Jukka, Viinamäki Heimo   +3 more
doaj   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]

, 2017
The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover, Juan J. Carrero, null null, Pablo Molina, Pablo Ureña Torres, Philippe Chauveau, Sandro Mazzaferro   +6 more
core   +2 more sources

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

Hygienic risk assessment of children with somatic health problems associated with vitamin deficiency

Analiz Riska Zdorovʹû, 2015
A study of the seasonal provision of children attending pre-school organizations that implement the standard artificial diet fortification with vitamins A, C, D, E, В 6 and B 12 was performed.
O.J. Ustinova, K.P. Luzhetskiy, S.A. Valina , Y.A. Ivashova   +3 more
doaj   +1 more source