Results 111 to 120 of about 19,034,701 (255)

Decreased vitamin B 12 and folic acid concentrations in acne patients after isotretinoin therapy: A controlled study

Indian Journal of Dermatology, 2014
Background: Oral isotretinoin treatment might influence the levels of vitamin B 12 and folic acid. Aims and Objectives: The aim of this study is to compare vitamin B 12 and folic acid levels in patients with moderate and severe acne vulgaris with those ...
Hilal Gökalp, I Bulur, M A Gürer
doaj   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Prenatal Vitamin D supplementation and child respiratory health: a randomised controlled trial [PDF]

, 2013
Background Observational studies suggest high prenatal vitamin D intake may be associated with reduced childhood wheezing. We examined the effect of prenatal vitamin D on childhood wheezing in an interventional study.
Hooper Richard, Richard Hooper, Shaheen Seif O., Warner, JO, Adrian R. Martineau (136644), Poulton, S, Martineau, AR, Goldring, ST, Seif O. Shaheen (177559), Yu, C, Sheree Poulton, Janet Stocks (425915), Christina Yu, Stephen Robinson, Griffiths, CJ, Boyle, RJ, Hooper, R, Kirkby Jane C., Robinson Stephen, Robert J Boyle, Stephen T Goldring, Martineau Adrian R., Warner John O., John O Warner, Goldring Stephen T., Yu Christina, Stocks, J, Chris J. Griffiths (425910), Stocks Janet, Boyle Robert J., Jane C. Kirkby (425914), Janet Stocks, Richard Hooper (425916), Kirkby, JC, Christina Yu (425912), Stephen Robinson (425911), Robinson, S, Shaheen, SO, Jane C Kirkby, Stephen T. Goldring (425909), Poulton Sheree, John O. Warner (425917), Adrian R Martineau, Seif O Shaheen, Robert J. Boyle (425918), Griffiths Chris J., Chris J Griffiths, Sheree Poulton (425913)   +47 more
core   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Efficacy of Early Neonatal Vitamin A Supplementation in Reducing Mortality During Infancy in Ghana, India and Tanzania: Study Protocol for a Randomized Controlled Trial. [PDF]

, 2012
Vitamin A supplementation of 6-59 month old children is currently recommended by the World Health Organization based on evidence that it reduces mortality.
Honorati Masanja, Fontaine Olivier, Bahl, Rajiv, Dube Brinda, Rajiv Bahl, Oleary Maureen, Taneja, Sunita, Fawzi Wafaie, Msham Salum, Martines Jose, NEOVITA Study Author Group, Kirkwood, BR, Bhandari, Nita, Oleary, M, Sam Newton, Salum Msham, Newton Sam, Bhandari, N, Brinda Dube, Bahl, R, Emily Smith, Dube, Brinda, Fawzi, W, Mazumder, S, Sarmila Mazumder, Oleary, Maureen, Shannon, C, Kirkwood Betty R, Betty R Kirkwood, Martines, J, Taneja Sunita, Msham, Salum, Jose Martines, Masanja, H, null null, Olivier Fontaine, Msham, S, Mazumder, Sarmila, Fontaine, O, Nita Bhandari, Edmond, Karen, Ruben, Julia, Sunita Taneja, Kaur Jasmine, Wafaie Fawzi, Smith, E, Masanja Honorati, Taneja, S, Ruben Julia, Yoshida, Sachiyo, Bhandari Nita, Karen Edmond, Caitlin Shannon, Fontaine, Olivier, Smith Emily, Maureen Oleary, Kaur, Jasmine, Ruben, J, Julia Ruben, Fawzi, Wafaie, Newton, S, Newton, Sam, Edmond Karen, Mazumder Sarmila, Martines, Jose, Kirkwood, Betty R., Kirkwood, Betty R, Bahl Rajiv, Jasmine Kaur, Shannon Caitlin, Edmond, K, Sachiyo Yoshida, Masanja, Honorati, Shannon, Caitlin, Smith, Emily, Dube, B, Yoshida, S, Kaur, J, Yoshida Sachiyo   +78 more
core   +2 more sources

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Association of vitamin D, B-12 and Calcium levels in middle age women presenting with body aches and pains Vitamin D, B-12 and Calcium levels in aches and pains

Pakistan Armed Forces Medical Journal
Objective: To determine the association of vitamin D, B-12 and Calcium levels in middle age women presenting with body aches and pains Study Design: Comparative cross-sectional study Place and Duration of Study: General medicine department, Pak ...
Syed Sarosh Jamal Peerzada, Khurram Haq Nawaz, Muhammad Zahid Hussain, Hamad Khan, Syed Umer Shah, Hamid Mukhtar Butt   +5 more
doaj   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Dental Implants Rehabilitation in Patients with Vitamin D3 Imbalance: A Randomized Controlled Trial

Applied Sciences
Background: Vitamin D3 is an important factor for bone metabolism, and its deficiency may affect dental implantation results. Materials and methods: 384 patients with a diagnosis of tooth loss and vitamin D deficiency were examined and treated with ...
Ekaterina Diachkova, Marina Skachkova, Yuryi Zhilkov, Magamed Kerimov, Svetlana Tarasenko, Anna Babkova, Natalia Zhukova, Svetlana Bokareva, Silvio Taschieri, Alexey Unkovskiy, Olesya Kytko, Viktoria Zaborova, Elizaveta Kytko, Stefano Corbella   +13 more
doaj   +1 more source