Results 171 to 180 of about 305,395 (350)

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source

Comparison Of Vitamin B12 Level Among Vegetarian And Non Vegetarian Apparently Healthy Individuals In District Tharparkar

Journal of Bahria University Medical and Dental College, 2012
Objective: Subjects adopting a vegetarian diet are liable to vitamin B12 deficiency. The current work was undertaken to investigate vitamin B12 status in apparently healthy vegetarians in Mithi, district Tharparkar, Sindh.
Aneel Kapoor, Nudrat Anwar Zuberi, Muktiar Baig   +2 more
doaj  

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo, Kunzhao Huang, Xiaoyuan Yi, Pei Lu, Huaying Xie, Wen Li, Qingyu Zeng, Feifei He, Duo Wang, Liyan Wang   +9 more
wiley   +1 more source

The transcobalamin receptor knockout mouse: a model for vitamin B ₁₂ deficiency in the central nervous system

, 2013
Shao‐Chiang Lai, Yasumi Nakayama, Jeffrey M. Sequeira, Bogdan J. Wlodarczyk, Robert M. Cabrera, Richard H. Finnell, Teodoro Bottiglieri, Edward V. Quadros   +7 more
openalex   +1 more source

Prevalence of iron and Vitamin B ₁₂ deficiencies and inflammatory anemia in treatment-naive patients with cancer: A cross-sectional study

, 2020
Avinash Pandey, Raj Aryan, Krishna Murari, Shivkant Singh, Piyush Pankaj   +4 more
openalex   +1 more source

Vitamin B-12 Deficiency Induces Anomalies of Base Substitution and Methylation in the DNA of Rat Colonic Epithelium [PDF]

, 2004
Sang‐Woon Choi, Simonetta Friso, Haifa Ghandour, Pamela J. Bagley, Jacob Selhub, Joel B. Mason   +5 more
openalex   +1 more source

Vitamin B₁₂status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls

, 2021
Agata Sobczyńska‐Malefora, Edgard Delvin, Andrew McCaddon, Kourosh R. Ahmadi, Dominic J. Harrington   +4 more
openalex   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Helicobacter pyloriassociated vitamin B₁₂deficiency, pernicious anaemia and subacute combined degeneration of the spinal cord [PDF]

, 2013
H. Basavana Gowdappa, M Mahesh, Kalpana Babu, MG Narahari   +3 more
openalex   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source