Results 271 to 280 of about 948,114 (320)

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Sports Supplement Analysis Survey for the Prevalence of WADA Prohibited Substances in the Australian Online Marketplace

Drug Testing and Analysis, EarlyView.
A survey of 200 sports supplements purchased online in Australia and analysed for WADA Prohibited Substances. Athlete education regarding the use of sports supplements remains a high priority as 35% of the products contained WADA Prohibited Substances. ABSTRACT Sports supplements are used extensively by people involved in competitive sports. However, a
Louise Barker, Adam Cawley, Naomi Speers, Kerry Knowler, Karina Chilman   +4 more
wiley   +1 more source

Advancing aqueous zinc‐ion batteries with carbon dots: A comprehensive review

EcoEnergy, EarlyView.
Carbon dots (CDs), with their distinctive structure and superior electrochemical properties, represent an innovative class of carbon‐based materials with broad potential applications for optimizing aqueous zinc‐ion batteries (AZIBs) performance. This comprehensive review highlights the potential application of CDs in AZIBs.
Mingying Chen, Junjie Ma, Yanhong Feng, Quanping Yuan, Yinghong Wu, Yifan Liu, Guangzhi Hu, Xijun Liu   +7 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

N‐terminal pro‐brain natriuretic peptide and cardiorenal outcome in patients with anaemia in chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 848-858, April 2025.
Abstract Aims Blood levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) may be modified by low renal clearance and anaemia. The aim of this study was to investigate the impact of the blood NT‐proBNP level on cardiovascular and renal outcomes in patients with these two manifestations.
Hiroshi Nishi, Masaomi Nangaku, Tadashi Sofue, Tatsuo Kagimura, Ichiei Narita   +4 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Identifying Typical Presentations of Vitamin B-12 Deficiency among Individuals Attending Tertiary Care Hospital in Central Gujarat: A Case Control Study.

Sangita Patel, Alpesh B. Makwana, Archana U. Gandhi, Latika T. Chugh, Vipul Bhavsar   +4 more
openalex   +1 more source

Prevalence of Vitamin B-12 Deficiency in Type 2 Diabetes Mellitus Patients

M. V. Jali, Sanjay Kambar, Sujata Jali, Shridhar C. Ghagane   +3 more
openalex   +1 more source

Systemic Lupus Erythematosus Associated with Mixed-Type Autoimmune Hemolytic Anaemia and Vitamin B 12 Deficiency - A Case Report

Dipa Yadav, Avinash Yadav, Shalika R. Bhandari, Umesh Kumar Singh   +3 more
openalex   +1 more source

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Psychosis in Vitamin B12 Deficiency

Archives of Internal Medicine, 1971
Vitamin B 12 deficiency may present with a psychosis which is curable if treated promptly. 1-8 Although this fact is not new and is described in various textbooks, 9,10 it seems that it is often forgotten, which results in prolonged suffering from irreversible brain damage.
Paul R. McCurdy, Richard J. Hart
openaire   +3 more sources