Results 81 to 90 of about 1,065,947 (371)
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan+4 more
wiley +1 more source
Diagnosing vitamin B-12 deficiency on the basis of serum B-12 assay [PDF]
Serum vitamin B-12 concentrations are measured to assess the presence of its deficiency in patients presenting with haematolological, neurological, and neuropsychiatric abnormalities. Replacement therapy is instituted promptly, particularly to prevent irreversible neurological and cognitive dysfunction.
openaire +3 more sources
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim+9 more
wiley +1 more source
Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity. The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population.
Hossein Khedmat+3 more
doaj +1 more source
Evidence from web-based dietary search patterns to the role of B12 deficiency in chronic pain [PDF]
Profound vitamin B12 deficiency is a known cause of disease, but the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms as well as the relationship of eating meat and B12 levels is unclear.
arxiv +1 more source
The impact of niobium doping upon the magnetotransport properties of the oxygen-deficient perovskite SrCo1-xNbxO3-d [PDF]
The oxygen-deficient perovskite cobaltite SrCo1-xNbxO3-d was synthesized by direct solid-state reaction and its magnetotransport properties were investigated. This cobaltite exhibits an unusual ferromagnetic behavior with a transition temperature Tm = 130-150 K and a spin glass like behavior below Tm.
arxiv +1 more source
Psychiatric Manifestation of Vitamin B-12 Deficiency: An Update [PDF]
Psychiatric manifestations of vitamin B-12 deficiency are reviewed from 1986 to the present. Specific clinical entities reviewed include depression, organic psychosis, obsessive-compulsive disorder, childhood manifestations and dementia.
Edwards, M.D., C. Stephen+2 more
core +1 more source
Overview of a roundtable on NHANES monitoring of biomarkers of folate and vitamin B-12 status: measurement procedure issues123456 [PDF]
A roundtable dialogue to discuss “NHANES Monitoring of Biomarkers of Folate and Vitamin B-12 Status” took place in July 2010. This article provides an overview of the meeting and this supplement issue. Although the focus of the roundtable dialogue was on
Coates, Paul M+2 more
core +2 more sources
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
On deficiency problems for graphs [PDF]
Motivated by analogous questions in the setting of Steiner triple systems and Latin squares, Nenadov, Sudakov and Wagner [Completion and deficiency problems, Journal of Combinatorial Theory Series B, 2020] recently introduced the notion of graph deficiency. Given a global spanning property $\mathcal P$ and a graph $G$, the deficiency $\text{def}(G)$ of
arxiv