Advanced Science, EarlyView.A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi +8 more
wiley +1 more source
Role of Carnosine in Combination With Vitamin B Complex in Preventing the Progression of Diabetic Neuropathy in People With Type 2 Diabetes [PDF]
Mahitab Hany Hamouda +4 more
openalex +1 more source
Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity
Advanced Science, EarlyView.Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang +25 more
wiley +1 more source
The Vitamin B Complex and Fasting Blood-Sugar Levels: An Investigation into the Changes in Fasting Blood-Sugar Levels of Diabetic and Non-diabetic Patients Following the Intravenous Injection of Aneurin, Riboflavin and Nicotinamide, with a Review of Relevant Literature, and a Note on Diabetic Neuritis [PDF]
, 1949 Charles M. Wylie
openalex
Advanced Science, EarlyView.This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li +12 more
wiley +1 more source
Advanced Science, EarlyView.This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei +10 more
wiley +1 more source
An In Vitro Study of Effect of Water Soluble Vitamin B Complex on Antimicrobial Activity of Antibiotics against Klebsiella species Isolated from Respiratory Samples [PDF]
, 2017 Sowmya Nasimuddin +5 more
openalex +1 more source
Bioprospecting of probiotics with antimicrobial activities against Salmonella Heidelberg and that produce B-complex vitamins as potential supplements in poultry nutrition [PDF]
, 2020 Sabrina da Silva Sabo +9 more
openalex +1 more source
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source