ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie+11 more
wiley +1 more source
Introducción: la Ataxia Espinocerebelosa tipo 2 (SCA2) es una enfermedad neurodegenerativa severa que representa un serio problema de salud en Cuba, debido a las altas tasas de prevalencia e incidencia y a la ausencia de tratamientos curativos. Objetivos:
Luis Velázquez-Pérez+10 more
doaj
The Role of Vitamin B Complex in Periodontal Disease: A Systematic Review Examining Supplementation Outcomes, Age Differences in Children and Adults, and Aesthetic Changes. [PDF]
Buzatu R, Luca MM, Bumbu BA.
europepmc +1 more source
Egg Production in Pullets on Diet Containing Synthetic Vitamin B Complex Supplement
Thomas H. Jukes, E. L. R. Stokstad
openalex +1 more source
The Effect of Methylated Vitamin B Complex on Depressive and Anxiety Symptoms and Quality of Life in Adults with Depression [PDF]
John E. Lewis+7 more
openalex +1 more source
Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen+7 more
wiley +1 more source
Vitamin B Complex Encapsulation in Bacterial Nanocellulose: A Novel System for Heat and Chemical Stabilization in Food Products. [PDF]
Sánchez-Osorno DM+4 more
europepmc +1 more source
Pulse Radiolysis Studies on the Reaction of the Reduced Vitamin B12 Complex Cob(II)alamin with Superoxide [PDF]
Rohan S. Dassanayake+2 more
openalex +1 more source
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai+9 more
wiley +1 more source
A PILOT STUDY TO ASSESS THE EFFICACY AND SAFETY OF FOLIC ACID AND/OR VITAMIN B COMPLEX ON HEPATITIS C INFECTED PATIENTS TREATED WITH PEGYLATED INTERFERON AND RIBAVIRIN [PDF]
Nermeen Ashoush
openalex +1 more source